ERAF: Difference between revisions

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{{Infobox_gene}}
{{GNF_Protein_box
'''Alpha-hemoglobin-stabilizing protein''' is a [[protein]] that in humans is encoded by the ''ERAF'' [[gene]].<ref name="pmid11231637">{{cite journal | vauthors = Miele G, Manson J, Clinton M | title = A novel erythroid-specific marker of transmissible spongiform encephalopathies | journal = Nat Med | volume = 7 | issue = 3 | pages = 361–4 |date=Mar 2001 | pmid = 11231637 | pmc =  | doi = 10.1038/85515 }}</ref><ref name="pmid12066189">{{cite journal | vauthors = Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachi K, Simon MC, Blobel GA, Weiss MJ | title = An abundant erythroid protein that stabilizes free alpha-haemoglobin | journal = Nature | volume = 417 | issue = 6890 | pages = 758–63 |date=Jun 2002 | pmid = 12066189 | pmc =  | doi = 10.1038/nature00803 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ERAF erythroid associated factor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51327| accessdate = }}</ref>
| image = PBB_Protein_ERAF_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1w09.
| PDB = {{PDB2|1w09}}, {{PDB2|1w0a}}, {{PDB2|1w0b}}, {{PDB2|1xzy}}, {{PDB2|1y01}}, {{PDB2|1z8u}}
| Name = Erythroid associated factor
| HGNCid = 18075
| Symbol = ERAF
| AltSymbols =; AHSP; EDRF
| OMIM = 605821
| ECnumber =
| Homologene = 9605
| MGIid =
  | GeneAtlas_image1 = PBB_GE_ERAF_219672_at_tn.png
| Function = {{GNF_GO|id=GO:0030492 |text = hemoglobin binding}} {{GNF_GO|id=GO:0051082 |text = unfolded protein binding}}
| Component = {{GNF_GO|id=GO:0005833 |text = hemoglobin complex}}
| Process = {{GNF_GO|id=GO:0006457 |text = protein folding}} {{GNF_GO|id=GO:0020027 |text = hemoglobin metabolic process}} {{GNF_GO|id=GO:0030097 |text = hemopoiesis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 51327
    | Hs_Ensembl = ENSG00000169877
    | Hs_RefseqProtein = NP_057717
    | Hs_RefseqmRNA = NM_016633
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 31446680
    | Hs_GenLoc_end = 31447624
    | Hs_Uniprot = Q9NZD4
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Erythroid associated factor''', also known as '''ERAF''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ERAF erythroid associated factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51327| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Florio P, Rossi M, Sigurdardottir M, ''et al.'' |title=Paracrine regulation of endometrial function: interaction between progesterone and corticotropin-releasing factor (CRF) and activin A. |journal=Steroids |volume=68 |issue= 10-13 |pages= 801-7 |year= 2004 |pmid= 14667971 |doi=  }}
*{{cite journal  | author=Florio P |title=Paracrine regulation of endometrial function: interaction between progesterone and corticotropin-releasing factor (CRF) and activin A |journal=Steroids |volume=68 |issue= 10–13 |pages= 801–7 |year= 2004 |pmid= 14667971 |doi=10.1016/S0039-128X(03)00137-5  |name-list-format=vanc| author2=Rossi M  | author3=Sigurdardottir M  | display-authors=3  | last4=Ciarmela  | first4=Pasquapina  | last5=Luisi  | first5=Stefano  | last6=Viganò  | first6=Paola  | last7=Grasso  | first7=Daniela  | last8=Fiore  | first8=Giovina  | last9=Cobellis  | first9=Luigi }}
*{{cite journal  | author=Weiss MJ, Zhou S, Feng L, ''et al.'' |title=Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia. |journal=Ann. N. Y. Acad. Sci. |volume=1054 |issue=  |pages= 103-17 |year= 2006 |pmid= 16339656 |doi= 10.1196/annals.1345.013 }}
*{{cite journal  | author=Weiss MJ |title=Role of alpha-hemoglobin-stabilizing protein in normal erythropoiesis and beta-thalassemia |journal=Ann. N. Y. Acad. Sci. |volume=1054 |issue=  |pages= 103–17 |year= 2006 |pmid= 16339656 |doi= 10.1196/annals.1345.013 |name-list-format=vanc| author2=Zhou S  | author3=Feng L  | display-authors=3  | last4=Gell  | first4=David A.  | last5=MacKay  | first5=Joel P.  | last6=Shi  | first6=Yigong  | last7=Gow  | first7=Andrew J. }}
*{{cite journal  | author=Zhang QH, Ye M, Wu XY, ''et al.'' |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546-60 |year= 2001 |pmid= 11042152 |doi= }}
*{{cite journal  | author=Zhang QH |title=Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546–60 |year= 2001 |pmid= 11042152 |doi=10.1101/gr.140200 | pmc=310934  |name-list-format=vanc| author2=Ye M  | author3=Wu XY  | display-authors=3 | last4=Ren  | first4=SX  | last5=Zhao  | first5=M | last6=Zhao  | first6=CJ  | last7=Fu  | first7=G  | last8=Shen  | first8=Y  | last9=Fan  | first9=HY  }}
*{{cite journal | author=Miele G, Manson J, Clinton M |title=A novel erythroid-specific marker of transmissible spongiform encephalopathies. |journal=Nat. Med. |volume=7 |issue= 3 |pages= 361-4 |year= 2001 |pmid= 11231637 |doi= 10.1038/85515 }}
*{{cite journal  | author=Gell D |title=Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40602–9 |year= 2002 |pmid= 12192002 |doi= 10.1074/jbc.M206084200 |name-list-format=vanc| author2=Kong Y  | author3=Eaton SA  | display-authors=3  | last4=Weiss  | first4=MJ  | last5=MacKay  | first5=JP }}
*{{cite journal | author=Kihm AJ, Kong Y, Hong W, ''et al.'' |title=An abundant erythroid protein that stabilizes free alpha-haemoglobin. |journal=Nature |volume=417 |issue= 6890 |pages= 758-63 |year= 2002 |pmid= 12066189 |doi= 10.1038/nature00803 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Gell D, Kong Y, Eaton SA, ''et al.'' |title=Biophysical characterization of the alpha-globin binding protein alpha-hemoglobin stabilizing protein. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40602-9 |year= 2002 |pmid= 12192002 |doi= 10.1074/jbc.M206084200 }}
*{{cite journal  | author=Viprakasit V |title=Evaluation of alpha hemoglobin stabilizing protein (AHSP) as a genetic modifier in patients with beta thalassemia |journal=Blood |volume=103 |issue= 9 |pages= 3296–9 |year= 2004 |pmid= 14715623 |doi= 10.1182/blood-2003-11-3957 |name-list-format=vanc| author2=Tanphaichitr VS  | author3=Chinchang W  | display-authors=3  | last4=Sangkla  | first4=P  | last5=Weiss  | first5=MJ  | last6=Higgs  | first6=DR }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Baudin-Creuza V |title=Transfer of human alpha- to beta-hemoglobin via its chaperone protein: evidence for a new state |journal=J. Biol. Chem. |volume=279 |issue= 35 |pages= 36530–3 |year= 2004 |pmid= 15220346 |doi= 10.1074/jbc.M405389200 |name-list-format=vanc| author2=Vasseur-Godbillon C  | author3=Pato C  | display-authors=3  | last4=Préhu  | first4=C  | last5=Wajcman  | first5=H  | last6=Marden  | first6=MC }}
*{{cite journal  | author=Viprakasit V, Tanphaichitr VS, Chinchang W, ''et al.'' |title=Evaluation of alpha hemoglobin stabilizing protein (AHSP) as a genetic modifier in patients with beta thalassemia. |journal=Blood |volume=103 |issue= 9 |pages= 3296-9 |year= 2004 |pmid= 14715623 |doi= 10.1182/blood-2003-11-3957 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Baudin-Creuza V, Vasseur-Godbillon C, Pato C, ''et al.'' |title=Transfer of human alpha- to beta-hemoglobin via its chaperone protein: evidence for a new state. |journal=J. Biol. Chem. |volume=279 |issue= 35 |pages= 36530-3 |year= 2004 |pmid= 15220346 |doi= 10.1074/jbc.M405389200 }}
*{{cite journal  | author=Gallagher PG |title=GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene |journal=J. Biol. Chem. |volume=280 |issue= 47 |pages= 39016–23 |year= 2006 |pmid= 16186125 |doi= 10.1074/jbc.M506062200 |name-list-format=vanc| author2=Liem RI  | author3=Wong E  | display-authors=3  | last4=Weiss  | first4=MJ  | last5=Bodine  | first5=DM }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-format=vanc| author2=Venkatesan K  | author3=Hao T  | display-authors=3  | last4=Hirozane-Kishikawa  | first4=Tomoko  | last5=Dricot  | first5=Amélie  | last6=Li  | first6=Ning  | last7=Berriz  | first7=Gabriel F.  | last8=Gibbons  | first8=Francis D.  | last9=Dreze  | first9=Matija }}
*{{cite journal  | author=Gallagher PG, Liem RI, Wong E, ''et al.'' |title=GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene. |journal=J. Biol. Chem. |volume=280 |issue= 47 |pages= 39016-23 |year= 2006 |pmid= 16186125 |doi= 10.1074/jbc.M506062200 }}
*{{cite journal  | author=Hamdane D |title=Reversible hexacoordination of alpha-hemoglobin-stabilizing protein (AHSP)/alpha-hemoglobin Versus pressure. Evidence for protection of the alpha-chains by their chaperone |journal=J. Biol. Chem. |volume=282 |issue= 9 |pages= 6398–404 |year= 2007 |pmid= 17194704 |doi= 10.1074/jbc.M610543200 |name-list-format=vanc| author2=Vasseur-Godbillon C  | author3=Baudin-Creuza V  | display-authors=3  | last4=Hoa  | first4=G. H. B.  | last5=Marden  | first5=M. C. }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | author=Hamdane D, Vasseur-Godbillon C, Baudin-Creuza V, ''et al.'' |title=Reversible hexacoordination of alpha-hemoglobin-stabilizing protein (AHSP)/alpha-hemoglobin Versus pressure. Evidence for protection of the alpha-chains by their chaperone. |journal=J. Biol. Chem. |volume=282 |issue= 9 |pages= 6398-404 |year= 2007 |pmid= 17194704 |doi= 10.1074/jbc.M610543200 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=51327}}
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{{protein-stub}}
{{gene-16-stub}}
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Revision as of 00:34, 31 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Alpha-hemoglobin-stabilizing protein is a protein that in humans is encoded by the ERAF gene.[1][2][3]


References

  1. ↑ Miele G, Manson J, Clinton M (Mar 2001). "A novel erythroid-specific marker of transmissible spongiform encephalopathies". Nat Med. 7 (3): 361–4. doi:10.1038/85515. PMID 11231637.
  2. ↑ Kihm AJ, Kong Y, Hong W, Russell JE, Rouda S, Adachi K, Simon MC, Blobel GA, Weiss MJ (Jun 2002). "An abundant erythroid protein that stabilizes free alpha-haemoglobin". Nature. 417 (6890): 758–63. doi:10.1038/nature00803. PMID 12066189.
  3. ↑ "Entrez Gene: ERAF erythroid associated factor".

Further reading



Retrieved from "https://www.wikidoc.org/index.php?title=ERAF&oldid=1417375"