CYP27C1: Difference between revisions

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(New page: {{protein |Name=cytochrome P450, family 27, subfamily C, polypeptide 1 |caption= |image= |width= |HGNCid=33480 |Symbol=CYP27C1 |AltSymbols= |EntrezGene=339761 |OMIM= |RefSeq=NM_001001665 |...)
 
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{{protein
{{Infobox_gene}}
|Name=cytochrome P450, family 27, subfamily C, polypeptide 1
|caption=
|image=
|width=
|HGNCid=33480
|Symbol=CYP27C1
|AltSymbols=
|EntrezGene=339761
|OMIM=
|RefSeq=NM_001001665
|UniProt= Q4G0S4
|PDB=
|ECnumber=
|Chromosome=2
|Arm=q
|Band=14.3
|LocusSupplementaryData=
}}
{{SI}}
{{EH}}


'''CYP27C1'''  ('''cy'''tochrome '''P'''450, family '''27''', subfamily '''C''', polypeptide '''1''') is a [[protein]] which in humans is encoded by the ''CYP27C1'' gene.<ref name="pmid14702039">{{cite journal | author = Ota T, Suzuki Y, Nishikawa T, ''et al'' | title = Complete sequencing and characterization of 21,243 full-length human cDNAs | journal = Nat. Genet. | volume = 36 | issue = 1 | pages = 40–5 | year = 2004 | month = January | pmid = 14702039 | doi = 10.1038/ng1285 | url = | issn = }}</ref><ref name="pmid15489334">{{cite journal | author = Gerhard DS, Wagner L, Feingold EA, ''et al'' | title = The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) | journal = Genome Res. | volume = 14 | issue = 10B | pages = 2121–7 | year = 2004 | month = October | pmid = 15489334 | pmc = 528928 | doi = 10.1101/gr.2596504 | url = | issn = }}</ref>
'''CYP27C1'''  ('''cy'''tochrome '''P'''450, family '''27''', subfamily '''C''', polypeptide '''1''') is a [[protein]] that in humans is encoded by the ''CYP27C1'' gene.<ref name="pmid14702039">{{cite journal | vauthors = Ota T, Suzuki Y, Nishikawa T | title = Complete sequencing and characterization of 21,243 full-length human cDNAs | journal = Nat. Genet. | volume = 36 | issue = 1 | pages = 40–5 |date=January 2004 | pmid = 14702039 | doi = 10.1038/ng1285 | url = | issn = |display-authors=etal}}</ref><ref name="pmid15489334">{{cite journal | vauthors = Gerhard DS, Wagner L, Feingold EA | title = The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) | journal = Genome Res. | volume = 14 | issue = 10B | pages = 2121–7 |date=October 2004 | pmid = 15489334 | pmc = 528928 | doi = 10.1101/gr.2596504 | url = | issn = |display-authors=etal}}</ref>


This gene encodes a member of the [[cytochrome P450]] superfamily of enzymes. The cytochrome P450 proteins are [[monooxygenase]]s which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.<ref name="entrez_2532">{{cite web | title = Entrez Gene: CYP39A1 | url =http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=339761 | accessdate = }}</ref>
This gene encodes a member of the [[cytochrome P450]] superfamily of enzymes. The cytochrome P450 proteins are [[monooxygenase]]s which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.<ref name="entrez_2532">{{cite web | title = Entrez Gene: CYP39A1 | url =https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=339761 | accessdate = }}</ref>
 
==Popular culture==
CYP27C1 is the topic of the comic [[Sherman's lagoon]] for May 26, 2016.<ref>{{cite web|url = http://shermanslagoon.com/comics/may-26-2016/|author = Jim Toomey|title = Sherman's lagoon| date = May 26, 2016}}</ref>  In response to Hawthorne's inquiry about the chemical, Ernest explains that it is an enzyme that enhances ability to see infrared light, allowing fish to see better in murky waters.  Ernest can see however that Hawthorne is more interested in how to synthesize it commercially.


==References==
==References==
{{Reflist}}
{{Reflist}}
==External links==
* {{UCSC gene info|CYP27C1}}
==Further reading==
{{refbegin | 2}}
*{{cite journal  |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |doi= 10.1073/pnas.242603899  |pmc=139241 |display-authors=etal}}
*{{cite journal  |vauthors=Nelson DR, Zeldin DC, Hoffman SM |title=Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. |journal=Pharmacogenetics |volume=14 |issue= 1 |pages= 1–18 |year= 2004 |pmid= 15128046 |doi=10.1097/00008571-200401000-00001  |display-authors=etal}}
{{refend}}


{{NLM content}}
{{NLM content}}
{{SIB}}
{{Cytochrome P450}}
{{Cytochrome P450}}


{{WH}}
 
{{WS}}
{{gene-2-stub}}

Latest revision as of 10:15, 30 August 2017

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Wikidata
View/Edit Human

CYP27C1 (cytochrome P450, family 27, subfamily C, polypeptide 1) is a protein that in humans is encoded by the CYP27C1 gene.[1][2]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.[3]

Popular culture

CYP27C1 is the topic of the comic Sherman's lagoon for May 26, 2016.[4] In response to Hawthorne's inquiry about the chemical, Ernest explains that it is an enzyme that enhances ability to see infrared light, allowing fish to see better in murky waters. Ernest can see however that Hawthorne is more interested in how to synthesize it commercially.

References

  1. ↑ Ota T, Suzuki Y, Nishikawa T, et al. (January 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  2. ↑ Gerhard DS, Wagner L, Feingold EA, et al. (October 2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  3. ↑ "Entrez Gene: CYP39A1".
  4. ↑ Jim Toomey (May 26, 2016). "Sherman's lagoon".

External links

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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