Chronic pancreatitis natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
Iqra Qamar (talk | contribs) |
Iqra Qamar (talk | contribs) |
||
| Line 14: | Line 14: | ||
==Complications== | ==Complications== | ||
*[[Diabetes]] | *[[Diabetes]]<ref name="pmid23890130">{{cite journal |vauthors=Rickels MR, Bellin M, Toledo FG, Robertson RP, Andersen DK, Chari ST, Brand R, Frulloni L, Anderson MA, Whitcomb DC |title=Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: recommendations from PancreasFest 2012 |journal=Pancreatology |volume=13 |issue=4 |pages=336–42 |year=2013 |pmid=23890130 |pmc=3830751 |doi=10.1016/j.pan.2013.05.002 |url=}}</ref> | ||
*Pseudocysts | *Pseudocysts | ||
*Bile duct or duodenal obstruction | *Bile duct or duodenal obstruction | ||
*Pancreatic ascites | *Pancreatic ascites<ref name="pmid2437177">{{cite journal |vauthors=Runyon BA |title=Amylase levels in ascitic fluid |journal=J. Clin. Gastroenterol. |volume=9 |issue=2 |pages=172–4 |year=1987 |pmid=2437177 |doi= |url=}}</ref><ref name="pmid12650789">{{cite journal |vauthors=Gómez-Cerezo J, Barbado Cano A, Suárez I, Soto A, Ríos JJ, Vázquez JJ |title=Pancreatic ascites: study of therapeutic options by analysis of case reports and case series between the years 1975 and 2000 |journal=Am. J. Gastroenterol. |volume=98 |issue=3 |pages=568–77 |year=2003 |pmid=12650789 |doi= |url=}}</ref> | ||
*Splenic vein thrombosis | *Pleural effusion | ||
*Pseudoaneurysms | *Splenic vein thrombosis<ref name="pmid1727767">{{cite journal |vauthors=Forsmark CE, Wilcox CM, Grendell JH |title=Endoscopy-negative upper gastrointestinal bleeding in a patient with chronic pancreatitis |journal=Gastroenterology |volume=102 |issue=1 |pages=320–9 |year=1992 |pmid=1727767 |doi= |url=}}</ref><ref name="pmid10773149">{{cite journal |vauthors=Sakorafas GH, Sarr MG, Farley DR, Farnell MB |title=The significance of sinistral portal hypertension complicating chronic pancreatitis |journal=Am. J. Surg. |volume=179 |issue=2 |pages=129–33 |year=2000 |pmid=10773149 |doi= |url=}}</ref><ref name="pmid1735356">{{cite journal |vauthors=Bernades P, Baetz A, Lévy P, Belghiti J, Menu Y, Fékété F |title=Splenic and portal venous obstruction in chronic pancreatitis. A prospective longitudinal study of a medical-surgical series of 266 patients |journal=Dig. Dis. Sci. |volume=37 |issue=3 |pages=340–6 |year=1992 |pmid=1735356 |doi= |url=}}</ref> | ||
*Pseudoaneurysms<ref name="pmid12559436">{{cite journal |vauthors=Beattie GC, Hardman JG, Redhead D, Siriwardena AK |title=Evidence for a central role for selective mesenteric angiography in the management of the major vascular complications of pancreatitis |journal=Am. J. Surg. |volume=185 |issue=2 |pages=96–102 |year=2003 |pmid=12559436 |doi= |url=}}</ref><ref name="pmid8129612">{{cite journal |vauthors=Arnaud JP, Bergamaschi R, Serra-Maudet V, Casa C |title=Pancreatoduodenectomy for hemosuccus pancreaticus in silent chronic pancreatitis |journal=Arch Surg |volume=129 |issue=3 |pages=333–4 |year=1994 |pmid=8129612 |doi= |url=}}</ref><ref name="pmid8301728">{{cite journal |vauthors=Wagner WH, Cossman DV, Treiman RL, Foran RF, Levin PM, Cohen JL |title=Hemosuccus pancreaticus from intraductal rupture of a primary splenic artery aneurysm |journal=J. Vasc. Surg. |volume=19 |issue=1 |pages=158–64 |year=1994 |pmid=8301728 |doi= |url=}}</ref> | |||
*Pancreatic cancer<ref name="pmid9091646">{{cite journal |vauthors=Lowenfels AB, Maisonneuve P, DiMagno EP, Elitsur Y, Gates LK, Perrault J, Whitcomb DC |title=Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group |journal=J. Natl. Cancer Inst. |volume=89 |issue=6 |pages=442–6 |year=1997 |pmid=9091646 |doi= |url=}}</ref> | |||
==Prognosis== | ==Prognosis== | ||
Revision as of 14:46, 2 November 2017
|
Chronic pancreatitis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
American Pancreatic Association Practice Guidelines |
|
Chronic pancreatitis natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Chronic pancreatitis natural history, complications and prognosis |
|
FDA on Chronic pancreatitis natural history, complications and prognosis |
|
CDC on Chronic pancreatitis natural history, complications and prognosis |
|
Chronic pancreatitis natural history, complications and prognosis in the news |
|
Blogs on Chronic pancreatitis natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Natural History
- The natural history of pain is highly variable and mostly involves intermittent pain attacks that decrease or resolve over 5-25 years while a few patients may have chronic pain.
- The average duration from the onset of symptoms until the establishment of the diagnosis of chronic pancreatitis in alcoholics is 62 months and 81 months in non-alcoholics.
- In alcohol-induced pancreatitis, the pain severity may be reduced by cessation of alcohol intake
Complications
- Diabetes[1]
- Pseudocysts
- Bile duct or duodenal obstruction
- Pancreatic ascites[2][3]
- Pleural effusion
- Splenic vein thrombosis[4][5][6]
- Pseudoaneurysms[7][8][9]
- Pancreatic cancer[10]
Prognosis
Some patients with chronic pancreatitis often look very sick, while others don't appear to be unhealthy at all. Considerable weight loss, due to malabsorption, is evident in a high percentage of patients, and can continue to be a health problem as the condition progresses.
References
- ↑ Rickels MR, Bellin M, Toledo FG, Robertson RP, Andersen DK, Chari ST, Brand R, Frulloni L, Anderson MA, Whitcomb DC (2013). "Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: recommendations from PancreasFest 2012". Pancreatology. 13 (4): 336–42. doi:10.1016/j.pan.2013.05.002. PMC 3830751. PMID 23890130.
- ↑ Runyon BA (1987). "Amylase levels in ascitic fluid". J. Clin. Gastroenterol. 9 (2): 172–4. PMID 2437177.
- ↑ Gómez-Cerezo J, Barbado Cano A, Suárez I, Soto A, Ríos JJ, Vázquez JJ (2003). "Pancreatic ascites: study of therapeutic options by analysis of case reports and case series between the years 1975 and 2000". Am. J. Gastroenterol. 98 (3): 568–77. PMID 12650789.
- ↑ Forsmark CE, Wilcox CM, Grendell JH (1992). "Endoscopy-negative upper gastrointestinal bleeding in a patient with chronic pancreatitis". Gastroenterology. 102 (1): 320–9. PMID 1727767.
- ↑ Sakorafas GH, Sarr MG, Farley DR, Farnell MB (2000). "The significance of sinistral portal hypertension complicating chronic pancreatitis". Am. J. Surg. 179 (2): 129–33. PMID 10773149.
- ↑ Bernades P, Baetz A, Lévy P, Belghiti J, Menu Y, Fékété F (1992). "Splenic and portal venous obstruction in chronic pancreatitis. A prospective longitudinal study of a medical-surgical series of 266 patients". Dig. Dis. Sci. 37 (3): 340–6. PMID 1735356.
- ↑ Beattie GC, Hardman JG, Redhead D, Siriwardena AK (2003). "Evidence for a central role for selective mesenteric angiography in the management of the major vascular complications of pancreatitis". Am. J. Surg. 185 (2): 96–102. PMID 12559436.
- ↑ Arnaud JP, Bergamaschi R, Serra-Maudet V, Casa C (1994). "Pancreatoduodenectomy for hemosuccus pancreaticus in silent chronic pancreatitis". Arch Surg. 129 (3): 333–4. PMID 8129612.
- ↑ Wagner WH, Cossman DV, Treiman RL, Foran RF, Levin PM, Cohen JL (1994). "Hemosuccus pancreaticus from intraductal rupture of a primary splenic artery aneurysm". J. Vasc. Surg. 19 (1): 158–64. PMID 8301728.
- ↑ Lowenfels AB, Maisonneuve P, DiMagno EP, Elitsur Y, Gates LK, Perrault J, Whitcomb DC (1997). "Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group". J. Natl. Cancer Inst. 89 (6): 442–6. PMID 9091646.