Arteriovenous malformation: Difference between revisions

Jump to navigation Jump to search
No edit summary
m (Bot: Adding CME Category::Cardiology)
 
(19 intermediate revisions by 3 users not shown)
Line 4: Line 4:
  | Image          = Cerebral arteriovenous malformation 1.jpeg
  | Image          = Cerebral arteriovenous malformation 1.jpeg
  | Caption        = Brain: Arteriovenous Malformation: Gross fixed tissue close-up view of malformation in meninges and cerebral cortex (an excellent example). <br> <small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] </small>
  | Caption        = Brain: Arteriovenous Malformation: Gross fixed tissue close-up view of malformation in meninges and cerebral cortex (an excellent example). <br> <small> [http://www.peir.net Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology] </small>
| DiseasesDB    = 15235
| ICD10          = {{ICD10|Q|27|3|q|20}}, {{ICD10|Q|28|0|q|20}}, {{ICD10|Q|28|2|q|20}}
| ICD9          = {{ICD9|747.6}}, {{ICD9|747.81}}
| ICDO          =
| OMIM          =
| MedlinePlus    =
| MeshID        = D001165
}}
}}
{{SI}}
{{Arteriovenous malformations}}
{{CMG}}; {{AE}}: {{KD}}
'''For patient information click [[Arteriovenous malformations (patient information)|here]]'''
'''''Synonyms and keywords:''''' '''AVM'''
==Overview==
'''Arteriovenous malformation''' is a [[congenital disorder]] of the connections between [[veins]] and [[arteries]] in the [[blood vessel|vascular system]]. The genetic transmission patterns of AVM (if any) are unknown, and AVM is not generally thought to be an inherited disorder--unless in the context of a specific hereditary [[syndrome]].


==Pathophysiology==
{{CMG}}; {{AE}} {{KD}}


Arteries and veins are part of the [[Circulatory system|human cardiovascular system]]. Normally, the arteries in the vascular system carry oxygen-rich blood at a relatively high pressure.  Structurally, arteries divide and sub-divide repeatedly, eventually forming a sponge-like [[capillary bed]].  Blood moves through the capillaries, giving up oxygen and taking up waste products from the surrounding cells. Capillaries successively join together, one upon the other, to form the veins that carry blood away at a relatively low pressure.  The heart acts to pump blood from the low pressure veins to the high pressure arteries.
{{SK}} AVM; arterio-venous malformations; arteriovenous malformations


If the capillary bed is thought of as a sponge, then an AVM is the rough equivalent of inserting a tangle of drinking straw|flexible soda straws from artery to vein through that sponge.  On an arteriogram, an AVM often resemble a tangle of spaghetti noodles. This tangle of blood vessels forms a relatively direct connection between high pressure arteries and low pressure veins and bypasses the capillary bed.
== [[Arteriovenous malformations overview|Overview]] ==


The result is a collection of blood vessels with abnormal connections and no [[Capillary|capillaries]]. This collection, often called a ''nidus'', can be extremely fragile and prone to bleeding. This bleeding can be catastrophic if it occurs in the brain, the lung or the gastrointestinal tract.
== [[Arteriovenous malformations historical perspective|Historical Perspective]] ==


AVMs can occur in various parts of the body
== [[Arteriovenous malformations classification|Classification]] ==


* [[human brain|Brain]], causing a [[cerebral arteriovenous malformation]]
== [[Arteriovenous malformations pathophysiology|Pathophysiology]] ==
* [[Spleen]]<ref name="pmid17145440">{{cite journal |author=Agrawal A, Whitehouse R, Johnson RW, Augustine T |title=Giant splenic artery aneurysm associated with arteriovenous malformation |journal=J. Vasc. Surg. |volume=44 |issue=6 |pages=1345–9 |year=2006|month=December |pmid=17145440 |doi=10.1016/j.jvs.2006.06.049|url=http://linkinghub.elsevier.com/retrieve/pii/S0741-5214(06)01369-3 |accessdate=2008-06-01}}</ref>
* [[Lung]]<ref name="pmid18294908">{{cite journal |author=Chowdhury UK, Kothari SS, Bishnoi AK, Gupta R, Mittal CM, Reddy S|title=Successful Lobectomy for Pulmonary Arteriovenous Malformation Causing Recurrent Massive Haemoptysis |journal=Heart Lung Circ |volume= |issue= |pages= |year=2008 |month=February |pmid=18294908 |doi=10.1016/j.hlc.2007.11.142|url=http://linkinghub.elsevier.com/retrieve/pii/S1443-9506(07)01113-4 |accessdate=2008-06-01}}</ref>
* [[Kidney]]<ref name="pmid16794894">{{cite journal |author=Barley FL, Kessel D, Nicholson T, Robertson I |title=Selective embolization of large symptomatic iatrogenic renal transplant arteriovenous fistula |journal=Cardiovasc Intervent Radiol|volume=29 |issue=6 |pages=1084–7 |year=2006 |pmid=16794894 |doi=10.1007/s00270-005-0265-z}}</ref>
* [[Spinal cord]]<ref name="pmid15730991">{{cite journal |author=Kishi K, Shirai S, Sonomura T, Sato M |title=Selective conformal radiotherapy for arteriovenous malformation involving the spinal cord |journal=Br J Radiol |volume=78 |issue=927 |pages=252–4|year=2005 |month=March |pmid=15730991 |doi= |url=http://bjr.birjournals.org/cgi/pmidlookup?view=long&pmid=15730991}}</ref>
* [[Liver]]<ref name="pmid7650340">{{cite journal |author=Bauer T, Britton P, Lomas D, Wight DG, Friend PJ, Alexander GJ|title=Liver transplantation for hepatic arteriovenous malformation in hereditary haemorrhagic telangiectasia |journal=J. Hepatol. |volume=22 |issue=5 |pages=586–90 |year=1995 |month=May |pmid=7650340 |doi=|url=http://linkinghub.elsevier.com/retrieve/pii/0168-8278(95)80455-2 |accessdate=2008-06-01}}</ref>
* [[Intercostal space]]<ref name="pmid17056881">{{cite journal |author=Rivera PP, Kole MK, Pelz DM, Gulka IB, McKenzie FN, Lownie SP |title=Congenital intercostal arteriovenous malformation |journal=AJR Am J Roentgenol |volume=187 |issue=5 |pages=W503–6|year=2006 |month=November |pmid=17056881 |doi=10.2214/AJR.05.0367 |url=http://www.ajronline.org/cgi/pmidlookup?view=long&pmid=17056881}}</ref>
* [[Iris (anatomy)|Iris]]<ref name="pmid16534057">{{cite journal |author=Shields JA, Streicher TF, Spirkova JH, Stubna M, Shields CL |title=Arteriovenous malformation of the iris in 14 cases |journal=Arch. Ophthalmol. |volume=124 |issue=3 |pages=370–5|year=2006 |month=March |pmid=16534057 |doi=10.1001/archopht.124.3.370 |url=http://archopht.ama-assn.org/cgi/pmidlookup?view=long&pmid=16534057}}</ref>
* [[Spermatic cord]]<ref name="pmid17939869">{{cite journal |author=Sountoulides P, Bantis A, Asouhidou I, Aggelonidou H|title=Arteriovenous malformation of the spermatic cord as the cause of acute scrotal pain: a case report |journal=J Med Case Reports |volume=1 |issue= |pages=110 |year=2007 |pmid=17939869 |doi=10.1186/1752-1947-1-110|url=http://www.jmedicalcasereports.com/content/1//110}}</ref>
=== Genetics ===
Can occur due to autosomal dominant diseases, such as Hereditary Hemorrhagic Telangiectasia


== Epidemiology and Demographics==
== [[Arteriovenous malformations causes|Causes]] ==


An estimated 300,000 Americans have AVMs, of which 12% (approximately 36,000) will exhibit symptoms that differ greatly in severity.
== [[Arteriovenous malformations differential diagnosis|Differentiating Arteriovenous malformations from other Diseases]] ==


==Diagnosis==
== [[Arteriovenous malformations epidemiology and demographics|Epidemiology and Demographics]] ==
===Symptoms ===
Symptoms of AVM vary according to the location of the malformation.  Roughly (88% -needs citation) AVM are asymptomatic; often the malformation is discovered as part of an [[autopsy]] or during treatment of an unrelated disorder (called in medicine an incidental finding), rarely its expansion or a micro-bleed from it, could cause epilepsy, deficit or elicit pain. 
The most general symptoms include
* [[Headache]]
* [[Epilepsy]],
* Difficulties with movement or coordination, including [[muscle weakness]] and even [[paralysis]];
* [[Vertigo (medical)|vertigo]] (dizziness);
* Difficulties of speech ([[dysarthria]]) and communication, such as [[alogia]];
* Difficulties with everyday activities, such as [[apraxia]];
* Abnormal sensations (numbness, tingling, or spontaneous [[pain]]);
* Memory and thought-related problems, such as [[confusion]], [[dementia]] or [[hallucination]]s.


== Treatment ==  
== [[Arteriovenous malformations risk factors|Risk Factors]] ==
Treatment can be symptomatic, or it can involve surgery or radiation therapy.


It can also be carried out via in interventinal radiography procedure using a glue to cut off the blood supply to the AVM.
== [[Arteriovenous malformations natural history, complications and prognosis|Natural History, Complications and Prognosis]] ==
== Research directions ==
The optimal management of AVMs remains an ongiong topic of clinical research. <ref>[http://www.cliniclog.com/arterio-venous_malformations.php Research trials in arterio-venous malformations; Rustam Al-Shahi Salman]</ref>.


==References==
== Diagnosis ==
{{reflist|2}}


[[Arteriovenous malformations history and symptoms|History and Symptoms]] | [[Arteriovenous malformations physical examination|Physical Examination]] | [[Arteriovenous malformations laboratory findings|Laboratory Findings]] | [[Arteriovenous malformations CT|CT]] | [[Arteriovenous malformations MRI|MRI]] | [[Arteriovenous malformations other imaging findings|Other Imaging Findings]] | [[Arteriovenous malformations other diagnostic studies|Other Diagnostic Studies]]


{{Congenital malformations and deformations of circulatory system}}
== Treatment ==
 
[[Arteriovenous malformations medical therapy|Medical Therapy]] | [[Arteriovenous malformations surgery|Surgery]] | [[Arteriovenous malformations primary prevention|Primary Prevention]] | [[Arteriovenous malformations secondary prevention|Secondary Prevention]] | [[Arteriovenous malformations cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Arteriovenous malformations future or investigational therapies|Future or Investigational Therapies]]


==Case Studies==
[[Arteriovenous malformations case study one|Case #1]]


[[Category:Congenital disorders]]
{{Congenital malformations and deformations of circulatory system}}
[[Category:Cardiology]]
[[Category:Neurology]]
[[Category:Needs patient information]]
[[Category:Disease]]


[[nl:arterioveneuze malformatie]]
[[nl:arterioveneuze malformatie]]
Line 83: Line 49:
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}
[[CME Category::Cardiology]]
[[Category:Congenital disorders]]
[[Category:Cardiology]]
[[Category:Neurology]]
[[Category:Disease]]

Latest revision as of 00:09, 15 March 2016

Arteriovenous malformation
Brain: Arteriovenous Malformation: Gross fixed tissue close-up view of malformation in meninges and cerebral cortex (an excellent example).
Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

Arteriovenous malformations Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Arteriovenous malformations from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Arteriovenous malformation On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Arteriovenous malformation

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Arteriovenous malformation

CDC on Arteriovenous malformation

Arteriovenous malformation in the news

Blogs on Arteriovenous malformation

Directions to Hospitals Treating Arteriovenous malformations

Risk calculators and risk factors for Arteriovenous malformation

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Synonyms and keywords: AVM; arterio-venous malformations; arteriovenous malformations

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Arteriovenous malformations from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

nl:arterioveneuze malformatie


Template:WikiDoc Sources CME Category::Cardiology