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| __NOTOC__
| | #REDIRECT [[Rosuvastatin#Contraindications]] |
| {{Rosuvastatin}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Contraindications==
| | [[Category: Cardiovascular Drugs]] |
| | | [[Category: Drug]] |
| CRESTOR is contraindicated in the following conditions:
| | [[Category: Statins]] |
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| *Patients with a known [[hypersensitivity]] to any component of this product. [[hypersensitivity]] reactions including [[rash]], [[pruritus]], [[urticaria]], and [[angioedema]] have been reported with CRESTOR [see Adverse Reactions (6.1)].
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| *Patients with active liver disease, which may include unexplained persistent elevations of hepatic transaminase levels [see Warnings and Precautions (5.2)].
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| *Women who are pregnant or may become pregnant. Because HMG‑CoA reductase inhibitors decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from [[cholesterol]], CRESTOR may cause fetal harm when administered to pregnant women. Additionally, there is no apparent benefit to therapy during pregnancy, and safety in pregnant women has not been established. If the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus and the lack of known clinical benefit with continued use during pregnancy [see *Use in Specific Populations (8.1) andNonclinical Toxicology (13.2)].
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| *Nursing mothers. Because another drug in this class passes into breast milk, and because HMG‑CoA reductase inhibitors have the potential to cause serious adverse reactions in nursing infants, women who require CRESTOR treatment should be advised not to nurse their infants [see Use in Specific Populations (8.3)].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = CRESTOR (ROSUVASTATIN CALCIUM) TABLET, FILM COATED [ASTRAZENECA PHARMACEUTICALS LP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bb0f3b5e-4bc6-41c9-66b9-6257e2513512 | publisher = | date = | accessdate = 17 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| {{Statins}}
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| [[Category:Statins]] | |
| [[Category:AstraZeneca]] | |
| [[Category:Carboxylic acids]] | |
| [[Category:Sulfonamides]]
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| [[Category:Pyrimidines]]
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| [[Category:Organofluorides]]
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