Cervical dysplasia classification: Difference between revisions
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{{Cervical dysplasia}} | {{Cervical dysplasia}} | ||
{{CMG}} | {{CMG}};{{AE}}{{SM}} | ||
==Classification== | ==Classification== | ||
Depending on several factors such as the type of HPV and the location of the infection, CIN can start in any of the three stage, and can either progress, or regress. | Depending on several factors such as the type of HPV and the location of the infection, CIN can start in any of the three stage, and can either progress, or regress. | ||
CIN is classified in grades: | CIN is classified in grades: | ||
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| '''CIN 1''' (Grade I) | | '''CIN 1''' (Grade I) | ||
| [[low grade squamous intraepithelial lesion|LSIL]]<ref name="Park">{{cite journal |author=Park J, Sun D, Genest D, Trivijitsilp P, Suh I, Crum C |title=Coexistence of low and high grade squamous intraepithelial lesions of the cervix: morphologic progression or multiple papillomaviruses? |journal=Gynecol Oncol |volume=70 |issue=3 |pages=386–91 |year=1998|pmid=9790792 |doi=10.1006/gyno.1998.5100}}</ref> | | [[low grade squamous intraepithelial lesion|LSIL]]<ref name="Park">{{cite journal |author=Park J, Sun D, Genest D, Trivijitsilp P, Suh I, Crum C |title=Coexistence of low and high grade squamous intraepithelial lesions of the cervix: morphologic progression or multiple papillomaviruses? |journal=Gynecol Oncol |volume=70 |issue=3 |pages=386–91 |year=1998|pmid=9790792 |doi=10.1006/gyno.1998.5100}}</ref> | ||
| The least risky type, represents only mild [[dysplasia]], or abnormal cell growth. | | The least risky type, represents only mild [[dysplasia]], or abnormal cell growth.It is confined to the basal 1/3 of the epithelium. This corresponds to infection with HPV, and typically will be cleared by immune response in a year or so, though can take several years to clear. | ||
| [[Image:Cervical_intraepithelial_neoplasia_(2)_koilocytosis.jpg|center|100px]] | | [[Image:Cervical_intraepithelial_neoplasia_(2)_koilocytosis.jpg|center|100px]] | ||
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| Moderate dysplasia confined to the basal 2/3 of the epithelium | | Moderate dysplasia confined to the basal 2/3 of the epithelium | ||
| [[Image: | | [[Image:100px-Cervical_intraepithelial_neoplasia_(3)_CIN2.jpg|center|100px]] | ||
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| '''CIN 3''' (Grade III) | | '''CIN 3''' (Grade III) | ||
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| Severe dysplasia that spans more than 2/3 of the epithelium, and may involve the full thickness. This lesion may sometimes also be referred to as cervical [[carcinoma in situ]]. | | Severe dysplasia that spans more than 2/3 of the epithelium, and may involve the full thickness. This lesion may sometimes also be referred to as cervical [[carcinoma in situ]]. | ||
| [[Image: | | [[Image:451px-Cervical_intraepithelial_neoplasia_(4)_CIN3.jpg|center|100px]] | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Needs content]] | [[Category:Needs content]] | ||
Latest revision as of 18:46, 17 August 2015
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Cervical dysplasia Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Cervical dysplasia classification On the Web |
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American Roentgen Ray Society Images of Cervical dysplasia classification |
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Risk calculators and risk factors for Cervical dysplasia classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shivali Marketkar, M.B.B.S. [2]
Classification
Depending on several factors such as the type of HPV and the location of the infection, CIN can start in any of the three stage, and can either progress, or regress.
CIN is classified in grades:
| Histology Grade | Corresponding Cytology | Description | Image |
|---|---|---|---|
| – | – | Normal cervical epithelium | _normal_squamous_epithelium.jpg) |
| CIN 1 (Grade I) | LSIL[1] | The least risky type, represents only mild dysplasia, or abnormal cell growth.It is confined to the basal 1/3 of the epithelium. This corresponds to infection with HPV, and typically will be cleared by immune response in a year or so, though can take several years to clear. | _koilocytosis.jpg) |
| CIN 2/3 | HSIL | Formerly subdivided into CIN2 and CIN3. | |
| CIN 2 (Grade II) | Moderate dysplasia confined to the basal 2/3 of the epithelium | _CIN2.jpg) | |
| CIN 3 (Grade III) | Severe dysplasia that spans more than 2/3 of the epithelium, and may involve the full thickness. This lesion may sometimes also be referred to as cervical carcinoma in situ. | _CIN3.jpg){kind=spacer} |
References
- ↑ Park J, Sun D, Genest D, Trivijitsilp P, Suh I, Crum C (1998). "Coexistence of low and high grade squamous intraepithelial lesions of the cervix: morphologic progression or multiple papillomaviruses?". Gynecol Oncol. 70 (3): 386–91. doi:10.1006/gyno.1998.5100. PMID 9790792.