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==Overview==
==Overview==
{{PAGENAME}} refers to a regimen consisting of [[fludarabine]], [[mitoxantrone]] and [[dexamethasone]] used to treat indolent [[non-Hodgkin's lymphoma]] and rituximab in combination is used for the treatment of advanced [[follicular lymphoma]]<ref name="pmid23960180">{{cite journal| author=Vitolo U, Ladetto M, Boccomini C, Baldini L, De Angelis F, Tucci A et al.| title=Rituximab maintenance compared with observation after brief first-line R-FND chemoimmunotherapy with rituximab consolidation in patients age older than 60 years with advanced follicular lymphoma: a phase III randomized study by the Fondazione Italiana Linfomi. | journal=J Clin Oncol | year= 2013 | volume= 31 | issue= 27 | pages= 3351-9 | pmid=23960180 | doi=10.1200/JCO.2012.44.8290 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23960180 }} </ref>
{{PAGENAME}} refers to a regimen consisting of [[fludarabine]], [[mitoxantrone]] and [[dexamethasone]] used to treat indolent [[non-Hodgkin's lymphoma]] and rituximab in combination is used for the treatment of advanced [[follicular lymphoma]]<ref name="pmid23960180">{{cite journal| author=Vitolo U, Ladetto M, Boccomini C, Baldini L, De Angelis F, Tucci A et al.| title=Rituximab maintenance compared with observation after brief first-line R-FND chemoimmunotherapy with rituximab consolidation in patients age older than 60 years with advanced follicular lymphoma: a phase III randomized study by the Fondazione Italiana Linfomi. | journal=J Clin Oncol | year= 2013 | volume= 31 | issue= 27 | pages= 3351-9 | pmid=23960180 | doi=10.1200/JCO.2012.44.8290 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23960180 }} </ref><ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C63454}}</ref>


==Regimen==
==Regimen==
{{chemo|F|Fludarabine}}


{{chemo|F|Fludarabine}}
{{chemo|N|Novantrone (mitoxantrone)}}
{{chemo|N|Novantrone (mitoxantrone)}}


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==Indications==
==Indications==
*[[Non-Hodgkin's lymphoma]]<ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C63454}}</ref><ref name="pmid23960180">{{cite journal| author=Vitolo U, Ladetto M, Boccomini C, Baldini L, De Angelis F, Tucci A et al.| title=Rituximab maintenance compared with observation after brief first-line R-FND chemoimmunotherapy with rituximab consolidation in patients age older than 60 years with advanced follicular lymphoma: a phase III randomized study by the Fondazione Italiana Linfomi. | journal=J Clin Oncol | year= 2013 | volume= 31 | issue= 27 | pages= 3351-9 | pmid=23960180 | doi=10.1200/JCO.2012.44.8290 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23960180 }} </ref>


*[[Non-Hodgkin's lymphoma]]<ref name="pmid23960180">{{cite journal| author=Vitolo U, Ladetto M, Boccomini C, Baldini L, De Angelis F, Tucci A et al.| title=Rituximab maintenance compared with observation after brief first-line R-FND chemoimmunotherapy with rituximab consolidation in patients age older than 60 years with advanced follicular lymphoma: a phase III randomized study by the Fondazione Italiana Linfomi. | journal=J Clin Oncol | year= 2013 | volume= 31 | issue= 27 | pages= 3351-9 | pmid=23960180 | doi=10.1200/JCO.2012.44.8290 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23960180 }} </ref>
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Chemotherapy regimens]]
[[Category:Chemotherapy regimens]]

Latest revision as of 18:03, 26 March 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:Fludarabine-Novantrone-Dexamethasone Regimen; FMD Regimen; FND Regimen

Overview

FN-D regimen refers to a regimen consisting of fludarabine, mitoxantrone and dexamethasone used to treat indolent non-Hodgkin's lymphoma and rituximab in combination is used for the treatment of advanced follicular lymphoma[1][2]

Regimen

FFludarabine

NNovantrone (mitoxantrone)

DDexamethasone

Indications

References

  1. 1.0 1.1 Vitolo U, Ladetto M, Boccomini C, Baldini L, De Angelis F, Tucci A; et al. (2013). "Rituximab maintenance compared with observation after brief first-line R-FND chemoimmunotherapy with rituximab consolidation in patients age older than 60 years with advanced follicular lymphoma: a phase III randomized study by the Fondazione Italiana Linfomi". J Clin Oncol. 31 (27): 3351–9. doi:10.1200/JCO.2012.44.8290. PMID 23960180.
  2. "NCI Thesaurus".
  3. "NCI Thesaurus".