Property:AnswerCExp
Jump to navigation
Jump to search
W
''' Incorrect ''' : Autosomal recessive inheritance of each heterozygous parent has a 50 percent likelihood of transmitting the mutation, so there is a 25 percent probability that an offspring will inherit two mutations. On average, 25 percent of siblings of affected subjects will be affected, 25 percent will harbor no mutations, and 50 percent will be carriers. +
''' Correct ''' : Skeletal surveys reveal punched-out lytic lesions, diffuse osteopenia, or fractures in nearly 80 percent of patients with MM at the time of diagnosis. +
''' Incorrect ''' : Immune-mediated HIT is associated with a fall in the platelet count of >50 percent that typically occurs 5 to 10 days after the initiation of heparin therapy which is not seen in this patient. +
''' Correct ''' : Patients who develop HIT will have an ongoing need for anticoagulation due to the HIT itself, and possibly due to the condition for which heparin was administered originally. Bivalirudin (Angiomax), a hemodialyzable direct thrombin inhibitor and Argatroban, a direct thrombin inhibitor should be initiated. +
''' Incorrect ''' : The first intervention in a patient with suspected HIT type 2 should be immediate cessation of all exposure to heparin and replacement with a suitable alternative anticoagulant as they are still at the risk of thrombosis. +
''' Correct ''' : In this patient the symptoms are as a result of increased amounts of plasma cells, as seen in Waldenstrom macroglobulinemia and in certain cases of multiple myeloma in which abnormal polymers of IgA, IgG, or kappa light chains are produced. +
''' Incorrect ''' : Patients with type 3 VWD, those with more severe type 1, and those with types 2A, 2B, and 2M disease often require replacement therapy with VWF, particularly in more serious bleeding situations when other measures have failed, or in settings when more prolonged treatment is required. +
C corresponds to argininosuccinate synthetase, which is an ATP-requiring enzyme that catalyzes the reaction that produces argininosuccinate. +
C corresponds to argininosuccinate synthetase, which catalyzes the the reaction that produces argininosuccinate from citrulline, aspartate, and ATP. +
OTC deficiency is a genetic disorder that is usually inherited in an X-linked recessive pattern. +
NADPH and NAD+ are cofactors for aldose reductase and sorbitol dehydrogenase, respectively. Both enzymes and their cofactors are involved in sorbitol metabolism. ATP is not a cofactor in either reaction. +
Cystinuria is inherited in an autosomal recessive pattern. Patients who manifest the disease have 2 mutant alleles, while carriers of the mutation have only 1 mutant allele. The offspring of an individual with the disease and an individual who carries the allele has a 50% chance of developing the disease. +
Incorrect
There is no difference in the medication needs between saphenous vein grafts and internal mammary artery grafts. +
Incorrect
Amiodarone is the recommended first line antiarrhythmic drug to maintain the normal sinus rhythm after being controlled in ED first. +
Correct
Amiodarone is the preferred class I anti arrhythmic drug for the maintenance of sinus rhythm. +