Bepridil

Bepridil
Gene therapy
Clinical data
Routes of; administration	Oral
ATC code	C08EA02 (WHO) ;
Physiological data
Legal status
Pharmacokinetic data
Bioavailability	Well absorbed
Protein binding	99%
Metabolism	Hepatic, CYP3A4-mediated
Elimination half-life	42 hours
Excretion	Renal
Identifiers
	IUPAC name (±)-(beta)-[(2-Methylpropoxy)methyl]-N-phenyl- N -(phenyl- methyl)-1-pyrrolidineethanamine;
CAS Number	64706-54-3;
PubChem Template:Abbreviation	2351;
DrugBank	APRD00727;
Chemical and physical data
Formula	C24H34N2O
Molar mass	421.02 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bepridil (trade name Vascor) is a calcium channel blocker once used to treat angina. It is no longer sold in the United States.

It is nonselective.^[1]

It has been discussed as a possible option in the treatment of atrial fibrillation.^[2]

It has been implicated in causing ventricular arrhythmia (Torsade de pointes).

Gene therapy

Clinical data
Routes of administration	Oral
ATC code	C08EA02 (WHO)
Physiological data
Legal status
Pharmacokinetic data
Bioavailability	Well absorbed
Protein binding	99%
Metabolism	Hepatic, CYP3A4-mediated
Elimination half-life	42 hours
Excretion	Renal
Identifiers
IUPAC name (±)-(beta)-[(2-Methylpropoxy)methyl]-N-phenyl- N -(phenyl- methyl)-1-pyrrolidineethanamine
CAS Number	64706-54-3
PubChem Template:Abbreviation	2351
DrugBank	APRD00727
Chemical and physical data
Formula	C₂₄H₃₄N₂O
Molar mass	421.02 g/mol