The heart in Crohn's disease

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Valvular Heart Disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor: Cafer Zorkun, M.D., Ph.D. [2]


Overview

Cardiac involvement in the course of inflammatory bowel disease (IBD) is considered very rare, and reports of endocardial[1] and valvular[2] involvement, myocarditis, [3] [4] pericardial effusion[5] [6] [7] and bradyarrhythmias[8] are few and sporadic. [9]

References

  1. Ward RL. Endocarditis complicating ulcerative colitis. Gastroenterology 1977; 73: 1189-90
  2. Burdick S, Tresch DD, Komokowski RA. Cardiac valvular dysfunction associated with Crohn's disease in the absence of ankylosing spondylitis. Am. Heart J. 1989; 118: 174-6.
  3. Nash CL, Panaccione R, Sutherland LR et al. Giant cell myocarditis, in a patient with Crohn's disease, treated with etanercept: a tumour necrosis factor-alpha antagonist. Can. J. Gastroenterol. 2001; 15: 607-11.
  4. Hyttinen L, Kaipiainen-Seppanen O, Halinen M. Recurrent myopericarditis in association with Crohn's disease. J. Intern. Med. 2003; 253: 386-8.
  5. Dubowitz M, Gorard DA. Cardiomyopathy and pericardial tamponade in ulcerative colitis. Eur. J. Gastroenterol. Hepatol. 2001; 13: 1255-8
  6. Sarrouj BJ, Zampino DJ, Cilursu AM. Pericarditis as the initial manifestation of inflammatory bowel disease. Chest 1994; 106: 1911-12
  7. Pang JA. Acute pericarditis. An unusual presentation of an exacerbation of ulcerative colitis. Med. J. Aust. 1985; 143: 356
  8. Ballinger A, Farthing MJ. Ulcerative colitis complicated by Wenckebach atrioventricular block. Gut 1992; 33: 1427-9
  9. Bragagni G, Brogna R, Franceschetti P, Zoli G. Cardiac Involvement in Crohn's Disease: Echocardiographic Study. J Gastroenterol Hepatol. 2007;22(1):18-22.

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