Periplasmic space

(Redirected from Periplasm)
Jump to navigation Jump to search

WikiDoc Resources for Periplasmic space

Articles

Most recent articles on Periplasmic space

Most cited articles on Periplasmic space

Review articles on Periplasmic space

Articles on Periplasmic space in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Periplasmic space

Images of Periplasmic space

Photos of Periplasmic space

Podcasts & MP3s on Periplasmic space

Videos on Periplasmic space

Evidence Based Medicine

Cochrane Collaboration on Periplasmic space

Bandolier on Periplasmic space

TRIP on Periplasmic space

Clinical Trials

Ongoing Trials on Periplasmic space at Clinical Trials.gov

Trial results on Periplasmic space

Clinical Trials on Periplasmic space at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Periplasmic space

NICE Guidance on Periplasmic space

NHS PRODIGY Guidance

FDA on Periplasmic space

CDC on Periplasmic space

Books

Books on Periplasmic space

News

Periplasmic space in the news

Be alerted to news on Periplasmic space

News trends on Periplasmic space

Commentary

Blogs on Periplasmic space

Definitions

Definitions of Periplasmic space

Patient Resources / Community

Patient resources on Periplasmic space

Discussion groups on Periplasmic space

Patient Handouts on Periplasmic space

Directions to Hospitals Treating Periplasmic space

Risk calculators and risk factors for Periplasmic space

Healthcare Provider Resources

Symptoms of Periplasmic space

Causes & Risk Factors for Periplasmic space

Diagnostic studies for Periplasmic space

Treatment of Periplasmic space

Continuing Medical Education (CME)

CME Programs on Periplasmic space

International

Periplasmic space en Espanol

Periplasmic space en Francais

Business

Periplasmic space in the Marketplace

Patents on Periplasmic space

Experimental / Informatics

List of terms related to Periplasmic space


The periplasmic space is the space seen between the plasma membrane and the outer membrane in the gram-negative bacteria. A very small periplasmic space between the plasma membrane and the peptidoglycan layer (cell wall) may be observed in the gram-positive bacteria (Zuber et al., 2006). The periplasmic space is a lot thicker in Gram negative bacteria. Periplasmic space may be filled with a loose network of peptidoglycan and may constitute up to 40% of the total cell volume. This space is involved in various biochemical pathways including nutrient acquisition, synthesis of peptidoglycan, electron transport, and alteration of substances toxic to the cell. Gram-positive bacteria do not have as many periplasmic proteins compared to the gram-negative bacteria. Instead gram-positive bacteria secrete enzymes which would normally be found in the periplasmic space of the gram-negative bacteria. This secreted enzyme is referred to as an exoenzyme. Substance that occupies the periplasmic space is referred to as a periplasm.

The periplasmic space is of particular clinical importance in that it is the site, in some species, that contains beta-lactamase, an enzyme responsible for degrading the penicillin group of antibiotic drugs, leading to penicillin resistance.

References: - D. White, The Physiology and Biochemistry of Prokaryotes, Oxford University Press, Oxford, 2000, pp. 22. - Zuber, B., Haenni, M., Ribeiro, T., Minnig, K., Lopes, F., Moreillon, P., Dubochet, J. 2006. Granular layer in the Periplasmic space of Gram-Positive bacteria and fine structures of Enterococcus gallinarum and Streptococcus gordonii septa revealed by Cryo-Electron Microscopy of vitreous sections. J. Bacteriol. Sept.;188 (18):6652-60


de:Periplasmatischer Raum

Template:WH Template:WS