Hyperkalaemic periodic paralysis

Jump to navigation Jump to search

WikiDoc Resources for Hyperkalaemic periodic paralysis

Articles

Most recent articles on Hyperkalaemic periodic paralysis

Most cited articles on Hyperkalaemic periodic paralysis

Review articles on Hyperkalaemic periodic paralysis

Articles on Hyperkalaemic periodic paralysis in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Hyperkalaemic periodic paralysis

Images of Hyperkalaemic periodic paralysis

Photos of Hyperkalaemic periodic paralysis

Podcasts & MP3s on Hyperkalaemic periodic paralysis

Videos on Hyperkalaemic periodic paralysis

Evidence Based Medicine

Cochrane Collaboration on Hyperkalaemic periodic paralysis

Bandolier on Hyperkalaemic periodic paralysis

TRIP on Hyperkalaemic periodic paralysis

Clinical Trials

Ongoing Trials on Hyperkalaemic periodic paralysis at Clinical Trials.gov

Trial results on Hyperkalaemic periodic paralysis

Clinical Trials on Hyperkalaemic periodic paralysis at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Hyperkalaemic periodic paralysis

NICE Guidance on Hyperkalaemic periodic paralysis

NHS PRODIGY Guidance

FDA on Hyperkalaemic periodic paralysis

CDC on Hyperkalaemic periodic paralysis

Books

Books on Hyperkalaemic periodic paralysis

News

Hyperkalaemic periodic paralysis in the news

Be alerted to news on Hyperkalaemic periodic paralysis

News trends on Hyperkalaemic periodic paralysis

Commentary

Blogs on Hyperkalaemic periodic paralysis

Definitions

Definitions of Hyperkalaemic periodic paralysis

Patient Resources / Community

Patient resources on Hyperkalaemic periodic paralysis

Discussion groups on Hyperkalaemic periodic paralysis

Patient Handouts on Hyperkalaemic periodic paralysis

Directions to Hospitals Treating Hyperkalaemic periodic paralysis

Risk calculators and risk factors for Hyperkalaemic periodic paralysis

Healthcare Provider Resources

Symptoms of Hyperkalaemic periodic paralysis

Causes & Risk Factors for Hyperkalaemic periodic paralysis

Diagnostic studies for Hyperkalaemic periodic paralysis

Treatment of Hyperkalaemic periodic paralysis

Continuing Medical Education (CME)

CME Programs on Hyperkalaemic periodic paralysis

International

Hyperkalaemic periodic paralysis en Espanol

Hyperkalaemic periodic paralysis en Francais

Business

Hyperkalaemic periodic paralysis in the Marketplace

Patents on Hyperkalaemic periodic paralysis

Experimental / Informatics

List of terms related to Hyperkalaemic periodic paralysis


Overview

Hyperkalaemic periodic paralysis is a genetic disorder which occurs in both humans and horses. It is characterized by muscle hyperexcitability or weakness which, exacerbated by potassium or cold, can lead to uncontrolled shaking followed by paralysis. Onset in humans usually occurs in the twenties.

The mutation which causes this disorder is dominant with linkage to the sodium channel expressed in muscle (called SCN4A). In the presence of high potassium levels, sodium channels fail to activate properly. The mutation causes single amino acid changes in parts of the channel which important for inactivation.

Equine hyperkalaemic periodic paralysis occurs in 1 in 50 quarter horses and can be traced to a single ancestor (A stallion named Impressive). Episodes in these horses are commonly brought on by alfalfa, which contains high levels of potassium.

See also


Template:WikiDoc Sources Template:WH