Yersinia pestis infection differential diagnosis: Difference between revisions

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__NOTOC__
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{{Yersinia pestis infection}}
{{Yersinia pestis infection}}
{{CMG}}; {{AE}} {{Rim}}
{{CMG}}; {{AE}} {{Rim}}; {{AJL}}


==Overview==
==Overview==
The differential diagnosis for ''yersina pestis'' infection depends on the clinical syndrome (bubonic plague, septicimic plague, pneumonic plague, or pharyngeal plague).  Bubonic plague should be differentiated from other causes of [[lymphadenopathy]], such as [[streptococcus|streptococcal]] or [[staphylococcus|staphylococcal]] [[lymphadenitis]], [[infectious mononucleosis]], [[cat-scratch fever]], and [[tularemia]].  Septicemic plague should be differentiated from non-specific [[sepsis]] syndrome and [[gram negative]] sepsis.  The differential diagnosis for pneumonic plague includes infections that cause [[community-acquired pneumonia]], such as [[pneumococcus|pneumococcal]] or [[streptococcus|streptococcal]] pneumonia, [[virus|viral]] pneumonia, [[hemophilus influenzae]], and [[anthrax]].<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
The differential diagnosis for ''yersina pestis'' infection is dependent on the clinical syndrome (bubonic plague, septicimic plague, pneumonic plague, or pharyngeal plague).  Bubonic plague should be differentiated from other causes of [[lymphadenopathy]], such as [[streptococcus|streptococcal]] or [[staphylococcus|staphylococcal]] [[lymphadenitis]], [[infectious mononucleosis]], [[cat-scratch fever]], and [[tularemia]].  Septicemic plague should be differentiated from non-specific [[sepsis]] syndrome and [[gram negative]] sepsis.  The differential diagnosis for pneumonic plague includes infections that cause [[community-acquired pneumonia]], such as [[pneumococcus|pneumococcal]] or [[streptococcus|streptococcal]] pneumonia, [[virus|viral]] pneumonia, [[hemophilus influenzae]], and [[anthrax]].<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
and Control. WHO/CDS/CSR/EDC/99.2 </ref>


==Differential Diagnosis==
==Differential Diagnosis==
===Bubonic Plague===
===Bubonic Plague===
Conditions that cause [[lymphadenopathy]]:<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
Conditions that also cause [[lymphadenopathy]]:<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
* Streptococcal or staphylococcal [[lymphadenitis]]
* Streptococcal or staphylococcal [[lymphadenitis]]
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* [[Tularemia]]
* [[Tularemia]]


Conditions that cause intra-abdominal [[lymphadenopathy]]:<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
Conditions that also cause intra-abdominal [[lymphadenopathy]]:<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
* [[Appendicitis]]
* [[Appendicitis]]
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* [[Enterocolitis]]
* [[Enterocolitis]]


Condition that causes inguinal [[lymphadenopathy]]:<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
Condition that also causes inguinal [[lymphadenopathy]]:<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
and Control. WHO/CDS/CSR/EDC/99.2 </ref>
* [[Inguinal hernia]]
* [[Inguinal hernia]]


===Septicemic Plague===
===Septicemic Plague===
Conditions that manifest similarly:
* Non-specific [[sepsis]] syndrome
* Non-specific [[sepsis]] syndrome
* [[Gram negative]] sepsis<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response
* [[Gram negative]] sepsis<ref name=WHObook>Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response

Revision as of 15:39, 25 July 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]; Alison Leibowitz [3]

Overview

The differential diagnosis for yersina pestis infection is dependent on the clinical syndrome (bubonic plague, septicimic plague, pneumonic plague, or pharyngeal plague). Bubonic plague should be differentiated from other causes of lymphadenopathy, such as streptococcal or staphylococcal lymphadenitis, infectious mononucleosis, cat-scratch fever, and tularemia. Septicemic plague should be differentiated from non-specific sepsis syndrome and gram negative sepsis. The differential diagnosis for pneumonic plague includes infections that cause community-acquired pneumonia, such as pneumococcal or streptococcal pneumonia, viral pneumonia, hemophilus influenzae, and anthrax.[1]

Differential Diagnosis

Bubonic Plague

Conditions that also cause lymphadenopathy:[1]

Conditions that also cause intra-abdominal lymphadenopathy:[1]

Condition that also causes inguinal lymphadenopathy:[1]

Septicemic Plague

Conditions that manifest similarly:

Pneumonic Plague

Infections that cause community-acquired pneumonia:[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Plague Manual: Epidemiology, Distribution, Surveillance. World Health Organization. Communicable Disease Surveillance and Response and Control. WHO/CDS/CSR/EDC/99.2



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