WBR0862

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Author [[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Pathology
Sub Category SubCategory::Pulmonology
Prompt [[Prompt::A 56 year old man presents to the neurology clinic for 3 weeks of upper and lower extremity weakness. The patient explains that he works as a plumber and that his everyday chores have become much harder since he has started to notice this weakness. Despite this, he has noticed a pattern that allows him to overcome it. He reports that the longer he is at rest, the weaker he feels, and as soon as he exerts himself he restores a lot of the strength in his extremities. Physical exam reveals 2/5 strength in all four extremities, bilateral eyelid ptosis, and absent deep tendon reflexes. With a certain diagnostic suspicion, the physician orders a chest CT that reveals a 2.5 cm mass adjacent to the left stem bronchus. Biopsy of the mass is likely to reveal which of the following findings?]]
Answer A AnswerA::Small dark blue neuroendocrine cells
Answer A Explanation AnswerAExp::
Answer B AnswerB::Keratin pearls and retracted cells
Answer B Explanation AnswerBExp::
Answer C AnswerC::Pleomorphic giant cells
Answer C Explanation AnswerCExp::
Answer D AnswerD::Granuloma formation with caseating necrosis
Answer D Explanation AnswerDExp::
Answer E AnswerE::Granuloma formation without caseating necrosis
Answer E Explanation AnswerEExp::
Right Answer RightAnswer::A
Explanation [[Explanation::

Educational Objective:
References: ]]

Approved Approved::No
Keyword WBRKeyword::Kulchitsky cells, WBRKeyword::small cell lung carcinoma, WBRKeyword::Lambert Eaton Myasthenic Syndrome, WBRKeyword::LEMS
Linked Question Linked::
Order in Linked Questions LinkedOrder::