VS ribozyme

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The Varkud satellite (VS) ribozyme carries out the cleavage of a phosphodiester bond [1].

Structure

The VS ribozyme is composed of 5 helices that form an H shape (helices II to VI). The first helix (I) contains the substrate cleavage site in the stem loop.

Species Distribution

The VS ribozyme has only been found in DNA of Neurospora mitochondria.

References

  1. Saville BJ, Collins RA (1990). "A site-specific self-cleavage reaction performed by a novel RNA in Neurospora mitochondria". Cell. 61 (4): 685–696.


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