Toxic shock syndrome other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview:

Although the best diagnostic tool for toxic shock syndrome (TSS) diagnosis is with clinical findings and laboratory exams, there are still some specific diagnostic ways to confirm TSS diagnosis.


Frozen-section biopsy

Early recognition of necrotizing fasciitis (NF) can be made by using of specimens of suspected areas of tissue ; however, it requires high expertise to process and interpret biopsy specimens, which is not readily available in most clinical settings where and when patients present[1].

Staphylococcus aureus antibody testing

Presence of Staphylococcus aureus in the absence of an acute-phase antibody can be highly suggestive of Staphylococcal TSS.

References

  1. Stamenkovic I, Lew PD (1984). "Early recognition of potentially fatal necrotizing fasciitis. The use of frozen-section biopsy". N. Engl. J. Med. 310 (26): 1689–93. doi:10.1056/NEJM198406283102601. PMID 6727947.


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