Toxic megacolon epidemiology and demographics

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Toxic Megacolon Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Epidemiology and Demographics

Incidence

  • The precise incidence of toxic megacolon is unknown in general population. The incidence of toxic megacolon in the associated disorders including ulceritive colitis and crohn's disease is:[1][2]

Mortality rate

  • The mortality rate of toxic megacolon associated with clostridium difficile is approximately %38-%80.[3][4]

Age

  • Patients of all age groups may develop toxic megacolon.

Race

  • There is no racial predilection described in toxic megacolon.

Gender

  • Toxic megacolon affects men and women equally.

Region

  • The majority of [disease name] cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

Developed Countries

Developing Countries

References

  1. Gan, S. Ian; Beck, P. L. (2003). "A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management". The American Journal of Gastroenterology. 98 (11): 2363–2371. doi:10.1111/j.1572-0241.2003.07696.x. ISSN 0002-9270.
  2. Grieco MB, Bordan DL, Geiss AC, Beil AR (1980). "Toxic megacolon complicating Crohn's colitis". Ann. Surg. 191 (1): 75–80. PMC 1344622. PMID 7352781.
  3. Hall JF, Berger D (2008). "Outcome of colectomy for Clostridium difficile colitis: a plea for early surgical management". Am. J. Surg. 196 (3): 384–8. doi:10.1016/j.amjsurg.2007.11.017. PMID 18519126.
  4. Earhart MM (2008). "The identification and treatment of toxic megacolon secondary to pseudomembranous colitis". Dimens Crit Care Nurs. 27 (6): 249–54. doi:10.1097/01.DCC.0000338869.70035.2b. PMID 18953191.

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