Thyroid cancer: Difference between revisions

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[[Thyroid cancer medical therapy|Medical therapy]] | [[Thyroid cancer surgery|Surgical options]] | [[Thyroid cancer primary prevention|Primary prevention]]  | [[Thyroid cancer secondary prevention|Secondary prevention]] | [[Thyroid cancer cost-effectiveness of therapy|Financial costs]] | [[Thyroid cancer future or investigational therapies|Future therapies]]
[[Thyroid cancer medical therapy|Medical therapy]] | [[Thyroid cancer surgery|Surgical options]] | [[Thyroid cancer primary prevention|Primary prevention]]  | [[Thyroid cancer secondary prevention|Secondary prevention]] | [[Thyroid cancer cost-effectiveness of therapy|Financial costs]] | [[Thyroid cancer future or investigational therapies|Future therapies]]


==Classification==
Thyroid cancers can be classified according to their pathological characteristics. The following variants can be distinguished (distribution over various subtypes may show regional variation):
* [[Papillary]] thyroid cancer (75%, incl. mixed papillary/follicular)
* [[Thyroid follicle|Follicular]] thyroid cancer (16%)
* [[Medullary]] thyroid cancer (5-7%)
* [[Anaplastic]] thyroid cancer (3%)
* [[Lymphoma]] (1%)
* [[Squamous cell carcinoma]], [[sarcoma]] (0.5 - 2%)
====Clinical features of medullary thyroid carcinoma====
The major clinical symptom of medullary thyroid carcinoma is [[diarrhea]]; occasionally a patient will have [[flushing]] episodes. Both occur particularly with [[liver]] [[metastasis]]. Occasionally, diarrhea or flushing will be the initial presenting complaint. The flushing that occurs in medullary thyroid carcinoma is indistinguishable from that associated with [[carcinoid]] syndrome. The presumed cause of flushing and diarrhea is the excessive production of [[calcitonin]] gene products ([[calcitonin]] or [[calcitonin gene-related peptide]]) and differs from the causation of flushing and diarrhea in [[carcinoid]] syndrome. Sites of spread of medullary thyroid carcinoma include local [[lymph nodes]] in the [[neck]], [[lymph nodes]] in the central portion of the [[chest]] ([[mediastinum]]), [[liver]], [[lung]], and [[bone]]. Spread to other sites such as skin or brain occurs but is uncommon.


==References==
==References==

Revision as of 20:32, 18 January 2012

For patient information click here Template:DiseaseDisorder infobox

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Michael Maddaleni, B.S.

Thyroid Cancer Main Page

Patient Information

Overview

Classification

Papillary Thyroid Cancer
Follicular Thyroid Cancer
Medullary Thyroid Cancer
Anaplastic Thyroid Cancer
Thyroid Lymphoma

Causes

Differential diagnosis

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Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes

Differentiating Thyroid cancer

Complications & Prognosis

Diagnosis

History and Symptoms | Physical Examination | Staging | Laboratory tests | Electrocardiogram | X Rays | CT | MRI Echocardiography or Ultrasound | Other images | Alternative diagnostics

Treatment

Medical therapy | Surgical options | Primary prevention | Secondary prevention | Financial costs | Future therapies


References

  • Bennedbæk F.N.; Perrild H.; Hegedüs L. (1999). "Diagnosis and treatment of the solitary thyroid nodule. Results of a European survey". Clinical Endocrinology. 50 (3): 357–363.
  • Carlo Ravetto, Luigia Colombo, Massimo E. Dottorini (2000). "Usefulness of fine-needle aspiration in the diagnosis of thyroid carcinoma". Cancer Cytopathology. 90 (6): 357–363.
  • Jacques Barbet, Loïc Campion, Françoise Kraeber-Bodéré, Jean-François Chatal, and the GTE Study Group (2005). "Prognostic Impact of Serum Calcitonin and Carcinoembryonic Antigen Doubling-Times in Patients with Medullary Thyroid Carcinoma". The Journal of Clinical Endocrinology & Metabolism. 90 (11): 6077–6084.

See also

External links

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