Thyroid cancer: Difference between revisions

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{{CMG}}; {{AE}} {{MJM}}; {{Ammu}}
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==Overview==
==Overview==
Thyroid cancer refers to any of four kinds of [[tumor]]s of the [[thyroid]] gland; Papillary, follicular, medullary and anaplastic. Papillary and follicular tumors are the most common and usually are [[benign tumor|benign]].  They grow slowly, may recur, but are generally not fatal in patients under 45 years of age. Medullary and anaplastic tumors are [[cancer|malignant]].  [[Medullary]] tumors have a good prognosis if restricted to the thyroid gland and a poorer prognosis if [[metastasis]] occurs.  Anaplastic tumors are fast-growing and respond poorly to therapy.
Thyroid [[nodule (medicine)|nodule]] are diagnosed by ultrasound guided [[fine needle aspiration]] or frequently by [[thyroidectomy]] (surgical removal and subsequent histological examination). As the thyroid cancer can uptake  [[iodine]], [[radioactive iodine]] is a commonly used modality in thyroid carcinomas. However, it is followed by [[TSH]] suppression by [[thyroxine]] therapy.
==Classification==
* The following flowchart depicts the classification of thyroid cancer.<ref name="pmid25810047">{{cite journal| author=Wells SA, Asa SL, Dralle H, Elisei R, Evans DB, Gagel RF et al.| title=Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. | journal=Thyroid | year= 2015 | volume= 25 | issue= 6 | pages= 567-610 | pmid=25810047 | doi=10.1089/thy.2014.0335 | pmc=PMC4490627 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25810047  }} </ref>
* The following flowchart depicts the classification of thyroid cancer.<ref name="pmid25810047">{{cite journal| author=Wells SA, Asa SL, Dralle H, Elisei R, Evans DB, Gagel RF et al.| title=Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. | journal=Thyroid | year= 2015 | volume= 25 | issue= 6 | pages= 567-610 | pmid=25810047 | doi=10.1089/thy.2014.0335 | pmc=PMC4490627 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25810047  }} </ref>
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Revision as of 20:31, 2 December 2015

Thyroid Cancer Main Page

Patient Information

Overview

Classification

Papillary Thyroid Cancer
Follicular Thyroid Cancer
Medullary Thyroid Cancer
Anaplastic Thyroid Cancer
Thyroid Lymphoma

Causes

Differential diagnosis

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Michael Maddaleni, B.S.; Ammu Susheela, M.D. [2]

Overview

Overview

Thyroid cancer refers to any of four kinds of tumors of the thyroid gland; Papillary, follicular, medullary and anaplastic. Papillary and follicular tumors are the most common and usually are benign. They grow slowly, may recur, but are generally not fatal in patients under 45 years of age. Medullary and anaplastic tumors are malignant. Medullary tumors have a good prognosis if restricted to the thyroid gland and a poorer prognosis if metastasis occurs. Anaplastic tumors are fast-growing and respond poorly to therapy. Thyroid nodule are diagnosed by ultrasound guided fine needle aspiration or frequently by thyroidectomy (surgical removal and subsequent histological examination). As the thyroid cancer can uptake iodine, radioactive iodine is a commonly used modality in thyroid carcinomas. However, it is followed by TSH suppression by thyroxine therapy.

Classification

  • The following flowchart depicts the classification of thyroid cancer.[1]
 
 
 
 
 
 
 
 
 
 
 
 
 
Thyroid cancer
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
​Papillary thyroid carcinoma
 
 
 
 
 
 
Follicular thyroid carcinoma
 
 
Medullary thyroid carcinoma
 
Anaplastic thyroid carcinoma
 
 
 
 
Primary thyroid lymphoma
 
 
 
 

Reference

  1. Wells SA, Asa SL, Dralle H, Elisei R, Evans DB, Gagel RF; et al. (2015). "Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma". Thyroid. 25 (6): 567–610. doi:10.1089/thy.2014.0335. PMC 4490627. PMID 25810047.


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