Thrombotic thrombocytopenic purpura epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
The most proportion of [[Hemolytic-uremic syndrome|TTP]] cases occurred after 40 years. Congenital forms  occur in children.  
The most proportion of TTP cases occurred after 40 years, black race and femal sex. Congenital forms  occur in children.  


==Epidemiology and Demographics==
==Epidemiology and Demographics==

Revision as of 20:13, 27 September 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

The most proportion of TTP cases occurred after 40 years, black race and femal sex. Congenital forms occur in children.

Epidemiology and Demographics

Incidence

  • The incidence of acuired TTP is about 0.3 per 100,000 adult per year.[1]
  • Data suggests the increased risk of TTP in black race and femal sex.[2]

Prevalence

  • The incidence of TTP is approximately [number range] per 100,000 individuals worldwide.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
  • The prevalence of [disease/malignancy] is estimated to be [number] cases annually.

Case-fatality rate/Mortality rate

  • In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
  • The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

  • Patients of all age groups may developTTP.
  • The incidence of TTP increases with age; the median age at diagnosis is 40 years. TTP often occurs after 40 years.

Race

  • TTP usually affects individuals of theblack race.[3]

Gender

  • Females are more commonly affected by TTP than men. The females to men ratio is approximately 2 to 1.[3][4]

Region

  • The majority of TTP cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].


References

  1. Reese JA, Muthurajah DS, Kremer Hovinga JA, Vesely SK, Terrell DR, George JN (October 2013). "Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and clinical features". Pediatr Blood Cancer. 60 (10): 1676–82. doi:10.1002/pbc.24612. PMID 23729372.
  2. Terrell DR, Vesely SK, Kremer Hovinga JA, Lämmle B, George JN (November 2010). "Different disparities of gender and race among the thrombotic thrombocytopenic purpura and hemolytic-uremic syndromes". Am. J. Hematol. 85 (11): 844–7. doi:10.1002/ajh.21833. PMC 3420337. PMID 20799358.
  3. 3.0 3.1 Terrell DR, Vesely SK, Kremer Hovinga JA, Lämmle B, George JN (November 2010). "Different disparities of gender and race among the thrombotic thrombocytopenic purpura and hemolytic-uremic syndromes". Am. J. Hematol. 85 (11): 844–7. doi:10.1002/ajh.21833. PMC 3420337. PMID 20799358.
  4. Reese JA, Muthurajah DS, Kremer Hovinga JA, Vesely SK, Terrell DR, George JN (October 2013). "Children and adults with thrombotic thrombocytopenic purpura associated with severe, acquired Adamts13 deficiency: comparison of incidence, demographic and clinical features". Pediatr Blood Cancer. 60 (10): 1676–82. doi:10.1002/pbc.24612. PMID 23729372.

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