Thrombotic thrombocytopenic purpura differential diagnosis: Difference between revisions
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{{Thrombotic thrombocytopenic purpura}} | {{Thrombotic thrombocytopenic purpura}} | ||
{{CMG}} | {{CMG}} {{AE}} {{S.G.}} | ||
==Overview== | ==Overview== | ||
== Differential Diagnosis == | == Differential Diagnosis == | ||
The differential diagnosis of TTP | The main differential diagnosis of TTP is [[hemolytic-uremic syndrome]] (HUS; which has neurosymptoms, renal failure, hypertension and fever). Note that ADAMTS13 activity is normal in HUS.<ref name="JolyCoppo2017">{{cite journal|last1=Joly|first1=Bérangère S.|last2=Coppo|first2=Paul|last3=Veyradier|first3=Agnès|title=Thrombotic thrombocytopenic purpura|journal=Blood|volume=129|issue=21|year=2017|pages=2836–2846|issn=0006-4971|doi=10.1182/blood-2016-10-709857}}</ref> | ||
TTP must be differentiated from | |||
* TMA syndromes | |||
* Disseminated Intravascular Coagulation | |||
* Hypertension | |||
* Immune Thrombocytopenic Purpura (ITP) | |||
* Malignant Hypertension | |||
* Hematological abnormalities | |||
* Ischemic manifestations linked to autoimmune diseases | |||
===Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]=== | |||
On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6]. | |||
{| | |||
==References== | ==References== |
Revision as of 20:56, 13 September 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
Differential Diagnosis
The main differential diagnosis of TTP is hemolytic-uremic syndrome (HUS; which has neurosymptoms, renal failure, hypertension and fever). Note that ADAMTS13 activity is normal in HUS.[1]
TTP must be differentiated from
- TMA syndromes
- Disseminated Intravascular Coagulation
- Hypertension
- Immune Thrombocytopenic Purpura (ITP)
- Malignant Hypertension
- Hematological abnormalities
- Ischemic manifestations linked to autoimmune diseases
Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]
On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].
References
- ↑ Joly, Bérangère S.; Coppo, Paul; Veyradier, Agnès (2017). "Thrombotic thrombocytopenic purpura". Blood. 129 (21): 2836–2846. doi:10.1182/blood-2016-10-709857. ISSN 0006-4971.