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==Overview==
==Overview==
Thrombocytopenia can be divided into several categories based on its extent as well as its underlying etiology.
[[Thrombocytopenia]] can be divided into several categories based on its extent as well as its underlying [[etiology]].


==Classification==
==Classification==
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* moderate (50,000 to 99,000 per µL),
* moderate (50,000 to 99,000 per µL),
* severe (<50,000 per µL).   
* severe (<50,000 per µL).   
Note that these amounts may not be the same for every condition and one should interpreted them according to the underlying etiology of thrombocytopenia. For example, in immune thrombocytopenia [ITP], a platelet count of <30,000/µL represents severe thrombocytopenia and for gestational thrombocytopenia, a platelet count between 80,000 and 150,000/microL is considered as mild thrombocytopenia. Although one may instinctively assume that severe thrombocytopenia is associated with increased probability of bleeding and the subsequent need for treatment, such an association between platelet count and the risk of bleeding is not always predictable.
Note that these amounts may not be the same for every condition and one should interpreted them according to the underlying [[etiology]] of [[thrombocytopenia]]. For example, in [[Idiopathic thrombocytopenic purpura|idiopathic thrombocytopenia (ITP)]], a [[platelet]] count of <30,000/µL represents severe [[thrombocytopenia]] and for [[gestational thrombocytopenia]], a [[platelet]] count between 80,000 and 150,000/microL is considered as mild [[thrombocytopenia]]. Although one may instinctively assume that severe [[thrombocytopenia]] is associated with increased probability of bleeding and the subsequent need for treatment, such an association between platelet count and the risk of bleeding is not always predictable.


'''Based on etiology:'''
'''Based on etiology:'''

Revision as of 16:04, 24 June 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor-In-Chief: Farbod Zahedi Tajrishi

Overview

Thrombocytopenia can be divided into several categories based on its extent as well as its underlying etiology.

Classification

Based on platelet count:[1]

  • mild: (100,000 - 150,000 per µL), 
  • moderate (50,000 to 99,000 per µL),
  • severe (<50,000 per µL).

Note that these amounts may not be the same for every condition and one should interpreted them according to the underlying etiology of thrombocytopenia. For example, in idiopathic thrombocytopenia (ITP), a platelet count of <30,000/µL represents severe thrombocytopenia and for gestational thrombocytopenia, a platelet count between 80,000 and 150,000/microL is considered as mild thrombocytopenia. Although one may instinctively assume that severe thrombocytopenia is associated with increased probability of bleeding and the subsequent need for treatment, such an association between platelet count and the risk of bleeding is not always predictable.

Based on etiology:

References

  1. Williamson DR, Albert M, Heels-Ansdell D, Arnold DM, Lauzier F, Zarychanski R; et al. (2013). "Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes". Chest. 144 (4): 1207–1215. doi:10.1378/chest.13-0121. PMID 23788287.

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