Teratoma pathophysiology: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 8: Line 8:
==Pathophysiology==
==Pathophysiology==
===Pathogenesis===
===Pathogenesis===
*Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment.
*Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment.<ref name="VuralVural2015">{{cite journal|last1=Vural|first1=F.|last2=Vural|first2=B.|last3=Paksoy|first3=N.|title=Vaginal teratoma: A case report and review of the literature|journal=Journal of Obstetrics and Gynaecology|volume=35|issue=7|year=2015|pages=757–758|issn=0144-3615|doi=10.3109/01443615.2015.1004525}}</ref><ref name="El-MaarriRijlaarsdam2015">{{cite journal|last1=El-Maarri|first1=Osman|last2=Rijlaarsdam|first2=Martin A.|last3=Tax|first3=David M. J.|last4=Gillis|first4=Ad J. M.|last5=Dorssers|first5=Lambert C. J.|last6=Koestler|first6=Devin C.|last7=de Ridder|first7=Jeroen|last8=Looijenga|first8=Leendert H. J.|title=Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors|journal=PLOS ONE|volume=10|issue=4|year=2015|pages=e0122146|issn=1932-6203|doi=10.1371/journal.pone.0122146}}</ref>
*Mature teratoma comes from a single germ cell tumor after first phase of meiosis.<ref name="LinderMcCaw1975">{{cite journal|last1=Linder|first1=David|last2=McCaw|first2=Barbara Kaiser|last3=Hecht|first3=Frederick|title=Parthenogenic Origin of Benign Ovarian Teratomas|journal=New England Journal of Medicine|volume=292|issue=2|year=1975|pages=63–66|issn=0028-4793|doi=10.1056/NEJM197501092920202}}</ref>
*Mature teratoma comes from a single germ cell tumor after first phase of meiosis.<ref name="LinderMcCaw1975">{{cite journal|last1=Linder|first1=David|last2=McCaw|first2=Barbara Kaiser|last3=Hecht|first3=Frederick|title=Parthenogenic Origin of Benign Ovarian Teratomas|journal=New England Journal of Medicine|volume=292|issue=2|year=1975|pages=63–66|issn=0028-4793|doi=10.1056/NEJM197501092920202}}</ref>
*Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm).
*Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm).<ref name="El-MaarriRijlaarsdam2015">{{cite journal|last1=El-Maarri|first1=Osman|last2=Rijlaarsdam|first2=Martin A.|last3=Tax|first3=David M. J.|last4=Gillis|first4=Ad J. M.|last5=Dorssers|first5=Lambert C. J.|last6=Koestler|first6=Devin C.|last7=de Ridder|first7=Jeroen|last8=Looijenga|first8=Leendert H. J.|title=Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors|journal=PLOS ONE|volume=10|issue=4|year=2015|pages=e0122146|issn=1932-6203|doi=10.1371/journal.pone.0122146}}</ref>





Revision as of 19:43, 28 October 2019

Teratoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Teratoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Staging

Laboratory Findings

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Teratoma pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Teratoma pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Teratoma pathophysiology

CDC on Teratoma pathophysiology

Teratoma pathophysiology in the news

Blogs on Teratoma pathophysiology

Directions to Hospitals Treating Teratoma

Risk calculators and risk factors for Teratoma pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2]

Overview

The histopathology of teratoma depends on the histological subtype.Teratoma is a germ cell tumor due to abnormal development of pluripotent cells.

Pathophysiology

Pathogenesis

  • Mature teratoma arises from a pathological transformation of primordial germ cell during the develompment.[1][2]
  • Mature teratoma comes from a single germ cell tumor after first phase of meiosis.[3]
  • Mature teratoma contains a well differentiated tumor with all three germ layers (ectoderm, mesoderm and endoderm).[2]



References

  1. Vural, F.; Vural, B.; Paksoy, N. (2015). "Vaginal teratoma: A case report and review of the literature". Journal of Obstetrics and Gynaecology. 35 (7): 757–758. doi:10.3109/01443615.2015.1004525. ISSN 0144-3615.
  2. 2.0 2.1 El-Maarri, Osman; Rijlaarsdam, Martin A.; Tax, David M. J.; Gillis, Ad J. M.; Dorssers, Lambert C. J.; Koestler, Devin C.; de Ridder, Jeroen; Looijenga, Leendert H. J. (2015). "Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors". PLOS ONE. 10 (4): e0122146. doi:10.1371/journal.pone.0122146. ISSN 1932-6203.
  3. Linder, David; McCaw, Barbara Kaiser; Hecht, Frederick (1975). "Parthenogenic Origin of Benign Ovarian Teratomas". New England Journal of Medicine. 292 (2): 63–66. doi:10.1056/NEJM197501092920202. ISSN 0028-4793.

Template:WH Template:WS