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{{Systemic lupus erythematosus}}
{{Systemic lupus erythematosus}}


{{CMG}}; {{AE}} {{RT}}
{{CMG}}; {{AE}} {{MIR}} {{RT}}


==Overview==
==Overview==
'''Systemic Lupus Erythematosus''' ('''SLE''' or '''lupus''') is a chronic [[Autoimmunity|autoimmune disease]] that can be fatal, though with recent medical advances fatalities are becoming increasingly rare. As with other [[Autoimmunity|autoimmune diseases]], the [[immune system]] attacks the body’s cells and tissue, resulting in inflammation and tissue damage. <ref>{{cite web |url=http://www.lupus.org/education/stats.html#1 |title=LUPUS FOUNDATION OF AMERICA |accessdate=2007-07-04 |format= |work=}}</ref>


SLE can affect any part of the body, but most often harms the [[heart]], [[joint]]s, [[skin]], [[lung]]s, [[blood vessel]]s, [[liver]], [[kidney]]s and [[Nervous system#Vertebrates|nervous system]].<ref>{{cite web |url=http://www.lupus.org/education/stats.html#1 |title=LUPUS FOUNDATION OF AMERICA |accessdate=2007-07-04 |format= |work=}}</ref>
==Historical perspective==


The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non-European descent.<ref>{{cite web |url=http://www.lupus.org/education/stats.html#1 |title=LUPUS FOUNDATION OF AMERICA |accessdate=2007-07-04 |format= |work=}}</ref> Lupus is treatable [[Symptomatic treatment|symptomatically]], mainly with [[corticosteroid]]s and [[immunosuppression|immunosuppressants]], though there is currently no cure. However, many people with Lupus lead long and substantial lives.
==Classification==


==Pathophysiology==
==Differentiating Systemic lupus erythematosus from other diseases==
==Epidemiology and Demographics==
==Risk Factors==
==Screening==
==Natural history, complications and prognosis==
===Natural History===
===Complications===
===Prognosis===
==Diagnosis==
===Diagnostic criteria===
===History and Symptoms===
===Physical Examination===
===Laboratory Findings===
===Imaging Findings===
==Treatment==
===Medical Therapy===
===Surgery===
==Prevention==
===Primary Prevention===
===Secondary Prevention===
==References==
==References==
{{reflist|2}}
{{reflist|2}}
 
[[Category:Disease]]
[[Category:Arthritis]]
[[Category:Infectious disease]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Diseases involving the fasciae]]
[[Category:Poxviruses]]
[[Category:Rheumatology]]
[[Category:Sexually transmitted diseases]]
[[Category:Nephrology]]
[[Category:Autoimmune diseases]]
[[Category:Disease]]


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Revision as of 16:02, 1 August 2017

Title
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2] Raviteja Guddeti, M.B.B.S. [3]

Overview

Historical perspective

Classification

Pathophysiology

Differentiating Systemic lupus erythematosus from other diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural history, complications and prognosis

Natural History

Complications

Prognosis

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