Stomach cancer laboratory findings: Difference between revisions
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== Stomach cancer laboratory findings == | == Stomach cancer laboratory findings == | ||
* A complete blood cell count | * A [[Complete blood count|complete blood cell count]] shows [[anemia]]. | ||
* Liver function tests may be disturbed in | * [[Liver function tests]] may be disturbed in patients with liver metastasis. | ||
* Carcinoembryonic antigen (CEA) is elevated in 50% of patients | * [[Carcinoembryonic antigen]] (CEA) is elevated in 50% of patients. A drop in an elevated level of [[CEA]] means response to preoperative therapy but it is not sensitive or specific. | ||
* | * [[CA-125|Glycoprotein CA 125]] antigen may be elevated.<ref name="pmid280023202">{{cite journal| author=Luo T, Chen W, Wang L, Zhao H| title=CA125 is a potential biomarker to predict surgically incurable gastric and cardia cancer: A retrospective study. | journal=Medicine (Baltimore) | year= 2016 | volume= 95 | issue= 51 | pages= e5297 | pmid=28002320 | doi=10.1097/MD.0000000000005297 | pmc=5181804 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28002320 }}</ref> | ||
* [[CA19-9|Carbohydrate antigen 19-9]] (CA 19-9) is elevated.<ref name="pmid18821070">{{cite journal| author=Ucar E, Semerci E, Ustun H, Yetim T, Huzmeli C, Gullu M| title=Prognostic value of preoperative CEA, CA 19-9, CA 72-4, and AFP levels in gastric cancer. | journal=Adv Ther | year= 2008 | volume= 25 | issue= 10 | pages= 1075-84 | pmid=18821070 | doi=10.1007/s12325-008-0100-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18821070 }}</ref> | |||
* Cancer antigen 72-4 (CA72-4) may be elevated.<ref name="pmid7874576">{{cite journal| author=Guadagni F, Roselli M, Cosimelli M, Ferroni P, Spila A, Cavaliere F et al.| title=CA 72-4 serum marker--a new tool in the management of carcinoma patients. | journal=Cancer Invest | year= 1995 | volume= 13 | issue= 2 | pages= 227-38 | pmid=7874576 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7874576 }}</ref> | |||
* [[Alpha-fetoprotein]] (AFP) may be elevated.<ref name="pmid12435906">{{cite journal| author=Kono K, Amemiya H, Sekikawa T, Iizuka H, Takahashi A, Fujii H et al.| title=Clinicopathologic features of gastric cancers producing alpha-fetoprotein. | journal=Dig Surg | year= 2002 | volume= 19 | issue= 5 | pages= 359-65; discussion 365 | pmid=12435906 | doi=10.1159/000065838 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12435906 }}</ref> | |||
* Carbohydrate antigen 19-9 (CA 19-9) | |||
* Cancer antigen 72-4 (CA72-4) may be elevated | |||
* Alpha-fetoprotein (AFP) may be elevated | |||
==References== | ==References== | ||
Revision as of 18:27, 21 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
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Stomach cancer laboratory findings
- A complete blood cell count shows anemia.
- Liver function tests may be disturbed in patients with liver metastasis.
- Carcinoembryonic antigen (CEA) is elevated in 50% of patients. A drop in an elevated level of CEA means response to preoperative therapy but it is not sensitive or specific.
- Glycoprotein CA 125 antigen may be elevated.[1]
- Carbohydrate antigen 19-9 (CA 19-9) is elevated.[2]
- Cancer antigen 72-4 (CA72-4) may be elevated.[3]
- Alpha-fetoprotein (AFP) may be elevated.[4]
References
- ↑ Luo T, Chen W, Wang L, Zhao H (2016). "CA125 is a potential biomarker to predict surgically incurable gastric and cardia cancer: A retrospective study". Medicine (Baltimore). 95 (51): e5297. doi:10.1097/MD.0000000000005297. PMC 5181804. PMID 28002320.
- ↑ Ucar E, Semerci E, Ustun H, Yetim T, Huzmeli C, Gullu M (2008). "Prognostic value of preoperative CEA, CA 19-9, CA 72-4, and AFP levels in gastric cancer". Adv Ther. 25 (10): 1075–84. doi:10.1007/s12325-008-0100-4. PMID 18821070.
- ↑ Guadagni F, Roselli M, Cosimelli M, Ferroni P, Spila A, Cavaliere F; et al. (1995). "CA 72-4 serum marker--a new tool in the management of carcinoma patients". Cancer Invest. 13 (2): 227–38. PMID 7874576.
- ↑ Kono K, Amemiya H, Sekikawa T, Iizuka H, Takahashi A, Fujii H; et al. (2002). "Clinicopathologic features of gastric cancers producing alpha-fetoprotein". Dig Surg. 19 (5): 359–65, discussion 365. doi:10.1159/000065838. PMID 12435906.