Squamous cell carcinoma of the skin epidemiology and demographics: Difference between revisions

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* Cutaneous squamous cell carcinoma is the 2nd most common type of skin cancer in the United States, behind basal cell carcinoma (BCC), and accounts for approximately 20 percent of non melanoma skin cancers.<ref name="pmid11274625">{{cite journal| author=Alam M, Ratner D| title=Cutaneous squamous-cell carcinoma. | journal=N Engl J Med | year= 2001 | volume= 344 | issue= 13 | pages= 975-83 | pmid=11274625 | doi=10.1056/NEJM200103293441306 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11274625  }}</ref>  
* Cutaneous squamous cell carcinoma is the 2nd most common type of skin cancer in the United States, behind basal cell carcinoma (BCC), and accounts for approximately 20 percent of non melanoma skin cancers.<ref name="pmid11274625">{{cite journal| author=Alam M, Ratner D| title=Cutaneous squamous-cell carcinoma. | journal=N Engl J Med | year= 2001 | volume= 344 | issue= 13 | pages= 975-83 | pmid=11274625 | doi=10.1056/NEJM200103293441306 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11274625  }}</ref>  
* Because they are not typically reported to cancer registries, the exact incidence of this malignancy is unknown.
* Because they are not typically reported to cancer registries, the exact incidence of this malignancy is unknown.
=== Age ===
* The incidence of squamous cell carcinoma of the skin increases dramatically with age.
** It is infrequent in those under 45 years of age, although the incidence of cutaneous squamous cell carcinoma is increasing significantly in young individuals.
* For those over 75, the incidence is approximately 5 to 10 times higher than the incidence in younger age groups and 50 to 300 times higher than for those under 45.


=== Region ===
=== Region ===
* Squamous cell carcinoma is a common disease that tends to affect people living closer to the equator.
* Cutaneous squamous cell carcinoma is a common disease that tends to affect people living closer to the equator.
** In Australia, for example, there are approximately 1035 and 472 cases per 100,000 for men and women, respectively.<ref name="pmid8942434">{{cite journal| author=Green A, Battistutta D, Hart V, Leslie D, Weedon D| title=Skin cancer in a subtropical Australian population: incidence and lack of association with occupation. The Nambour Study Group. | journal=Am J Epidemiol | year= 1996 | volume= 144 | issue= 11 | pages= 1034-40 | pmid=8942434 | doi=10.1093/oxfordjournals.aje.a008875 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8942434  }}</ref>  
** In Australia, for example, there are approximately 1035 and 472 cases per 100,000 for men and women, respectively.<ref name="pmid8942434">{{cite journal| author=Green A, Battistutta D, Hart V, Leslie D, Weedon D| title=Skin cancer in a subtropical Australian population: incidence and lack of association with occupation. The Nambour Study Group. | journal=Am J Epidemiol | year= 1996 | volume= 144 | issue= 11 | pages= 1034-40 | pmid=8942434 | doi=10.1093/oxfordjournals.aje.a008875 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8942434  }}</ref>  
** In contrast, the age-adjusted incidences for men and women in Finland are only about 6 and 4 per 100,000.<ref name="pmid10411152">{{cite journal| author=Hannuksela-Svahn A, Pukkala E, Karvonen J| title=Basal cell skin carcinoma and other nonmelanoma skin cancers in Finland from 1956 through 1995. | journal=Arch Dermatol | year= 1999 | volume= 135 | issue= 7 | pages= 781-6 | pmid=10411152 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10411152  }}</ref>
** In contrast, the age-adjusted incidences for men and women in Finland are only about 6 and 4 per 100,000.<ref name="pmid10411152">{{cite journal| author=Hannuksela-Svahn A, Pukkala E, Karvonen J| title=Basal cell skin carcinoma and other nonmelanoma skin cancers in Finland from 1956 through 1995. | journal=Arch Dermatol | year= 1999 | volume= 135 | issue= 7 | pages= 781-6 | pmid=10411152 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10411152  }}</ref>

Revision as of 21:43, 22 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]

Overview

Epidemiology and Demographics

Incidence

  • Cutaneous squamous cell carcinoma is the 2nd most common type of skin cancer in the United States, behind basal cell carcinoma (BCC), and accounts for approximately 20 percent of non melanoma skin cancers.[1]
  • Because they are not typically reported to cancer registries, the exact incidence of this malignancy is unknown.

Age

  • The incidence of squamous cell carcinoma of the skin increases dramatically with age.
    • It is infrequent in those under 45 years of age, although the incidence of cutaneous squamous cell carcinoma is increasing significantly in young individuals.
  • For those over 75, the incidence is approximately 5 to 10 times higher than the incidence in younger age groups and 50 to 300 times higher than for those under 45.

Region

  • Cutaneous squamous cell carcinoma is a common disease that tends to affect people living closer to the equator.
    • In Australia, for example, there are approximately 1035 and 472 cases per 100,000 for men and women, respectively.[2]
    • In contrast, the age-adjusted incidences for men and women in Finland are only about 6 and 4 per 100,000.[3]

References

  1. Alam M, Ratner D (2001). "Cutaneous squamous-cell carcinoma". N Engl J Med. 344 (13): 975–83. doi:10.1056/NEJM200103293441306. PMID 11274625.
  2. Green A, Battistutta D, Hart V, Leslie D, Weedon D (1996). "Skin cancer in a subtropical Australian population: incidence and lack of association with occupation. The Nambour Study Group". Am J Epidemiol. 144 (11): 1034–40. doi:10.1093/oxfordjournals.aje.a008875. PMID 8942434.
  3. Hannuksela-Svahn A, Pukkala E, Karvonen J (1999). "Basal cell skin carcinoma and other nonmelanoma skin cancers in Finland from 1956 through 1995". Arch Dermatol. 135 (7): 781–6. PMID 10411152.


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