Squamous cell carcinoma of the lung epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]
Overview
Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers. It is the second most commonly encountered lung cancer after lung adenocarcinoma. Squamous cell carcinoma of the lung accounts for approximately 27% of all cancer deaths. The incidence of lung squamous-cell carcinoma increases with age; the median age at diagnosis is approximately 70 years (usually ranging from 65 to 74 years). Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1. Black race has a higher incidence of squamous cell lung carcinoma compared with White race.
Epidemiology and Demographics
Prevalence
- Squamous cell carcinoma of the lung is the second most common non-small cell lung cancer subtype in the United States.
- It accounts for 30% to 35% of all lung cancers.
- It accounts for approximately 27% of all cancer deaths.[1]
- The overall mortality from lung cancer (NSCLC and SCLC combined) in the United States in 2018 is 47.14 per 100,000 individuals.[2]
Incidence
- The annual incidence rate of lung squamous cell carcinoma is 14.4 per 100,000 individuals.
- The relative incidence rate of squamous cell carcinoma of the lung appears to be decreasing, compared to previous years.[1]
- The overall incidence of lung cancer (NSCLC and SCLC combined) in the United States in 2018 is 71.629 per 100,000 individuals.[3]
Age
- The incidence of squamous cell carcinoma of the lung increases with age; the median age at diagnosis is 70 years (usually ranging from 65 to 74 years).[4]
Gender
- Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1.
Race
- Black race has a higher incidence of squamous cell lung carcinoma compared with White race.[1]
References
- ↑ 1.0 1.1 1.2 Meza R, Meernik C, Jeon J, Cote ML (2015). "Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010". PLoS ONE. 10 (3): e0121323. doi:10.1371/journal.pone.0121323. PMC 4379166. PMID 25822850.
- ↑ American Cancer Society: Cancer Facts and Figures 2018. Atlanta, Ga: American Cancer Society, 2018. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf Exit Disclaimer. Last accessed January 5, 2018.
- ↑ American Cancer Society: Cancer Facts and Figures 2018. Atlanta, Ga: American Cancer Society, 2018. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf Exit Disclaimer. Last accessed January 5, 2018.
- ↑ Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R (2010). "Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis". J Thorac Oncol. 5 (1): 23–8. doi:10.1097/JTO.0b013e3181c41e8d. PMID 19934774.