Small intestine cancer medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2] Parminder Dhingra, M.D. [3]

Overview

Best treatment for curable small intestine cancer is surgical resection with combination of chemotherapy or radiotherapy. If tumor is not curable palliative surgery can be done.Chemotherapy is used to reduce the likelihood of metastasis developing, shrink tumor size, and slow tumor growth. Chemotherapy is often applied after surgery (adjuvant), before surgery (neo-adjuvant), or as primary therapy if surgery is not indicated (palliative). Other therapies include radiation and support therapies.

Treatment Strategy

  • The treatment of small intestine cancer is clinically challenging due to its delayed diagnosis. [1]
  • Main stay of the treatment is surgery for these tumors. [2].
  • Patients with small intestine cancer have many treatment options.
  • The selection depends on the the size and location of the tumor, metastasis and comorbidities.
  • The options are:
    • Surgery
    • Radiation therapy
    • Chemotherapy
    • Combination of methods and palliative treatment.
  • The capecitabine and oxaliplatin are found effective in some studies.[2]
  • Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities.
  • Because cancer treatments often damage healthy cells and tissues, side effects are common.
  • Side effect may not be the same for each person, and they may change from one treatment session to the next.

References

  1. Tang L, Huang LY, Cui J, Wu CR (June 2018). "Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases". Chin. Med. J. 131 (11): 1321–1326. doi:10.4103/0366-6999.232802. PMC 5987504. PMID 29786046.
  2. 2.0 2.1 Ogata Y, Yamaguchi K, Sasatomi T, Uchida S, Akagi Y, Shirouzu K (August 2010). "[Treatment and outcome in small bowel cancer]". Gan To Kagaku Ryoho (in Japanese). 37 (8): 1454–7. PMID 20716869.

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