Sickle-cell disease risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]

Overview

The most potent risk factor in the development of sickle-cell disease is race.

Risk Factors

The most potent risk factor in the development of sickle-cell disease is race, which include Africans, African Americans, Indians, and persons of Mediterranean descent. An additional risk factor is geographic location, with these locations containing the greatest occurrences of disease.