Sickle-cell disease risk factors: Difference between revisions
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{{Sickle-cell disease}} | {{Sickle-cell disease}} | ||
{{CMG}} {{AE}} {{shyam}} | {{CMG}} {{AE}} {{shyam}} | ||
==Overview== | |||
There are no specific risk factors for sickle cell disease. | |||
==Risk Factors== | ==Risk Factors== | ||
Revision as of 05:00, 5 September 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
There are no specific risk factors for sickle cell disease.
Risk Factors
Besides race, there are no specific risk factors for sickle cell disease. Sickle cell disease is a monogenetic disease, meaning that one gene mutations causes the disease. Thus environmental factors do not play a major role in acquisition of the disease. The disease occurs at birth after a person inherits 2 sickle cell alleles, one from each parent. Certain endemic regions contain a high prevalence of sickle cell alleles.[1]
There are some risk factors for precipitation of sickle cell crises, such as dehydration, low oxygen levels, medication nonadherence.
References
- ↑ Makani J, Ofori-Acquah SF, Nnodu O, Wonkam A, Ohene-Frempong K (2013). "Sickle cell disease: new opportunities and challenges in Africa". ScientificWorldJournal. 2013: 193252. doi:10.1155/2013/193252. PMC 3988892. PMID 25143960.