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Hepatic Laboratory Abnormalities—Study GS-US-540-5773 Remdesivir for 5 Days Remdesivir for 10 Days Total
ALT Increased Grade 3 8/194 (4%) 11/191 (6%) 19/385 (5%)
Grade 4 4/194 (2%) 5/191 (3%) 9/385 (2%)
AST Increased Grade 3 11/194 (6%) 7/190 (4%) 18/384 (5%)
Grade 4 3/194 (2%) 4/190 (2%) 7/384 (2%)
Total Bilirubin Increased Grade 3 1/193 (1%) 3/190 (2%) 4/383 (1%)
Grade 4 0 1/190 (1%) 1/383 (<1%)