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Suppurative thrombophlebitis usually occur in peripheral veins as a result of an intravenous catheter, or dissemination from a surrounding soft tissue infection . Other causes may include intravenous drug use, abrasions, lacerations, hypercoagulable states, and burns.

The high risk of suppurative thrombophlebitis in burn patients is explained by the high skin susceptibility to bacterial infection, use of broad spectrum antibiotics, and impairment of local defense due to loss of skin integrity.[1]

Lemierre's syndrome also known as jugular vein suppurative thrombophlebitis,postanginal sepsis, and necrobacillosis.[2] There is extension of the bacterial infection from pharyngitis, tonsillitis, or peri-tonsillar infection, to the carotid sheath vessels that contains the internal jugular vein resulting in inflammation, thrombosis, and infection.[3]


Vena cava suppurative thrombophlebitis usually occurs in central venous catheter settings

References

  1. Pruitt BA, McManus WF, Kim SH, Treat RC (1980). "Diagnosis and treatment of cannula-related intravenous sepsis in burn patients". Ann Surg. 191 (5): 546–54. PMC 1344732. PMID 7369818.
  2. Riordan T, Wilson M (2004). "Lemierre's syndrome: more than a historical curiosa". Postgrad Med J. 80 (944): 328–34. PMC 1743018. PMID 15192164.
  3. Sinave CP, Hardy GJ, Fardy PW (1989). "The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection". Medicine (Baltimore). 68 (2): 85–94. PMID 2646510.


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