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Chlamydial [[cervicitis]] in a female patient characterized by [[mucopurulent]] [[cervix|cervical]] discharge, [[erythema]], and [[inflammation]].]] Chlamydia is an asymptomatic disease for about 50-70% of the female population.  Of those who have an asymptomatic infection that is not detected by their doctor, approximately half will develop [[pelvic inflammatory disease]] (PID), a generic term for infection of the [[uterus]], [[fallopian tubes]], and/or [[ovaries]].
PID can cause scarring inside the [[reproductive organ]]s, which can later cause serious complications, including chronic [[pelvis|pelvic]] pain, difficulty becoming [[pregnancy|pregnant]], [[ectopic pregnancy|ectopic (tubal) pregnancy]], and other dangerous complications of pregnancy. Chlamydia causes 250,000 to 500,000 cases of PID every year in the U.S. Women infected with chlamydia are up to five times more likely to become infected with HIV, if exposed.<ref>{{cite web |url=http://www.cdc.gov/std/chlamydia/STDFact-Chlamydia.htm#complications |title=STD Facts - Chlamydia |accessdate=2007-10-26 |format= |work=}}</ref>
Chlamydia is known as the "Silent Epidemic" because in women, it may not cause any [[symptom]]s and will linger for months or years before being discovered. Symptoms that may occur include: unusual [[vagina]]l bleeding or discharge, pain in the abdomen, painful [[sexual intercourse]] ([[dyspareunia]]), [[fever]], painful [[urination]] or the urge to urinate more frequently than usual. Male patients may develop a white, cloudy or watery discharge (shown) from the tip of the [[penis]].]] In men, chlamydia shows symptoms in about 50% of cases. Symptoms that may occur include: a painful or burning sensation when urinating, an unusual discharge from the [[penis]], swollen or tender [[testicle]]s, or fever. Discharge, or the purulent exudate, is generally less viscous and lighter in color than for [[gonorrhea]]. If left untreated, it is possible for Chlamydia in men to spread to the testicles causing [[epididymitis]], which in rare cases can cause [[infertility|sterility]] if not treated within 6 to 8 weeks. Chlamydia causes more than 250,000 cases of epididymitis in the USA each year.
Chlamydia may also cause [[reactive arthritis]], especially in young men.  About 15,000 men develop reactive arthritis due to chlamydia infection each year in the USA, and about 5,000 are permanently affected by it. The triad of reactive arthritis, conjunctivitis and urethritis (inflammation of the urethra) is known as [[Reiter's Syndrome]].  All three entities must be present for this label to be used.  It can occur in both men and women, though is more common in men. 
As many as half of all [[infant]]s born to mothers with chlamydia will be born with the disease. Chlamydia can affect infants by causing spontaneous abortion; [[premature birth]]; [[conjunctivitis]], which may lead to [[blindness]]; and [[pneumonia]]. Conjunctivitis due to chlamydia typically occurs one week after birth (Compare with chemical causes (within hours) or gonorrhea (2-5 days)).


 
====Acute Sinusitis====
 
[[Acute (medical)|Acute]] sinusitis is usually precipitated by an earlier [[upper respiratory tract infection]], generally of [[virus|viral]] origin.
 
Virally damaged surface tissues are then colonized by [[bacteria]], most commonly ''[[Haemophilus influenzae]]'', ''[[Streptococcus pneumoniae]]'', ''[[Moraxella catarrhalis]]'' and ''[[Staphylococcus aureus]]''. Other [[bacterial]] [[pathogen]]s include other [[streptococci]] [[species]], [[Anaerobic organism|anaerobic bacteria]] and, less commonly, [[gram negative]] bacteria.
 
Another possible cause of sinusitis can be dental problems that affect the maxillary sinus.
 
[[Acute (medical)|Acute]] episodes of sinusitis can also result from [[fungus|fungal]] invasion.
 
These [[infection]]s are most often seen in [[patient]]s with [[diabetes]] or other [[immunodeficiency|immune deficiencies]] (such as [[AIDS]] or [[transplant]] [[patient]]s on anti-rejection medications) and can be life threatening. In type I diabetes, ketoacidosis causes sinusitis by [[Mucormycosis]].
 
 
 
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
|valign=top|
|+
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Subtypes of Myocarditis}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Histological Findings}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Clinical Presentation}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
:Fulminant
| style="padding: 5px 5px; background: #F5F5F5;" |
*Multiple foci of inflammation
| style="padding: 5px 5px; background: #F5F5F5;" |
*Acute severe cardiovascular compromise with ventricular dysfunction
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Acute
| style="padding: 5px 5px; background: #F5F5F5;" |
*''IDH1''
*''[[p53]]''
*Gene on chromosome 10q
*Gene on chromosome 17p
*Gene on chromosome 19q
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Chronic Active
| style="padding: 5px 5px; background: #F5F5F5;" |
*''[[EGFR]]''
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Chronic Persistent
| style="padding: 5px 5px; background: #F5F5F5;" |
*''[[TP53]]''
*''PDGFRA''
*''IDH1''
|-
|}

Revision as of 20:40, 8 March 2016

Acute Sinusitis

Acute sinusitis is usually precipitated by an earlier upper respiratory tract infection, generally of viral origin. Virally damaged surface tissues are then colonized by bacteria, most commonly Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis and Staphylococcus aureus. Other bacterial pathogens include other streptococci species, anaerobic bacteria and, less commonly, gram negative bacteria. Another possible cause of sinusitis can be dental problems that affect the maxillary sinus. Acute episodes of sinusitis can also result from fungal invasion. These infections are most often seen in patients with diabetes or other immune deficiencies (such as AIDS or transplant patients on anti-rejection medications) and can be life threatening. In type I diabetes, ketoacidosis causes sinusitis by Mucormycosis.