Sandbox Maliha: Difference between revisions
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*[[Hepatitis]] | *[[Hepatitis]] | ||
==Treatment== | |||
===Overview===Empiric antimicrobial therapy for Mycotic Aneurysm include intravenous [[Vancomycin]] and either [[Ceftriaxone]], [[Piperacillin-Tazobactam]] or [[Ciprofloxacin]] for 6 weeks. Alternative regimens include [[Cefepime[[, [[Imipenem-Cilastatin]], [[Meropenem]], or [[Ertapenem]] for Gram-negative bacteria. | |||
===Antimicrobial Regimen=== | |||
* '''Empiric antimicrobial therapy'''<ref>{{cite book | last = Gilbert | first = David | title = The Sanford guide to antimicrobial therapy 2014 | publisher = Antimicrobial Therapy | location = Sperryville, Va | year = 2014 | isbn = 978-1930808782 }}</ref> | |||
:* Preferred regimen: [[Vancomycin]] 2 g/day IV divided q6-12h targeting trough concentration of 15-20 μg/mL for 6 weeks (for critically ill patient, start with a loading dose of 25 mg/kg followed by 15 mg/kg q12h) {{and}} ([[Ceftriaxone]] 2 g IV q24h for 6 weeks {{or}} [[Piperacillin-Tazobactam]] 3.375 g IV q6h for 6 weeks {{or}} [[Ciprofloxacin]] 400 mg IV q12h for 6 weeks) | |||
:* Alternative regimen: Consider substituting [[Daptomycin]] for Vancomycin. Consider [[Cefepime]], [[Imipenem-Cilastatin]], [[Meropenem]], or [[Ertapenem]] for Gram-negative bacteria. | |||
The treatment for chronic fibrosing mediastinitis is somewhat controversial, and may include either steroids or surgical decompression of the affected vessels. | |||
Revision as of 18:50, 12 August 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Treatment
===Overview===Empiric antimicrobial therapy for Mycotic Aneurysm include intravenous Vancomycin and either Ceftriaxone, Piperacillin-Tazobactam or Ciprofloxacin for 6 weeks. Alternative regimens include [[Cefepime[[, Imipenem-Cilastatin, Meropenem, or Ertapenem for Gram-negative bacteria.
Antimicrobial Regimen
- Empiric antimicrobial therapy[1]
- Preferred regimen: Vancomycin 2 g/day IV divided q6-12h targeting trough concentration of 15-20 μg/mL for 6 weeks (for critically ill patient, start with a loading dose of 25 mg/kg followed by 15 mg/kg q12h) AND (Ceftriaxone 2 g IV q24h for 6 weeks OR Piperacillin-Tazobactam 3.375 g IV q6h for 6 weeks OR Ciprofloxacin 400 mg IV q12h for 6 weeks)
- Alternative regimen: Consider substituting Daptomycin for Vancomycin. Consider Cefepime, Imipenem-Cilastatin, Meropenem, or Ertapenem for Gram-negative bacteria.
The treatment for chronic fibrosing mediastinitis is somewhat controversial, and may include either steroids or surgical decompression of the affected vessels.
- ↑ Gilbert, David (2014). The Sanford guide to antimicrobial therapy 2014. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808782.