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| {{Lyme disease}}
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| {{CMG}};{{AE}}{{Anmol}}
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| ==Overview==
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| [[Magnetic resonance imaging|MRI]] is not helpful in diagnosis of [[Lyme disease]]. However, a [[Magnetic resonance imaging|MRI]] may be helpful in diagnosing [[Neurological|neurologic]] manifestation of [[Lyme disease history and symptoms|early and late disseminated Lyme disease]]. [[Magnetic resonance imaging|MRI]] scan in patients with [[neurological]] [[Lyme disease]] may demonstrate increased intensity in [[white matter]] at multiple foci on T2-weighted images suggesting [[demyelination]] or [[inflammatory]] changes. After [[antibiotic]] therapy, spontaneous resolution of [[Magnetic resonance imaging|MRI]] [[white matter]] hyper-intensities has been observed in [[Lyme disease]].
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| ==MRI==
| | {{CMG}}; {{AE}} {{Anmol}} |
| * Abnormal [[magnetic resonance imaging]] (MRI) findings are often seen in both [[Lyme disease history and symptoms|early and late disseminated Lyme disease]]. <ref name="pmid17729007">{{cite journal| author=Aalto A, Sjöwall J, Davidsson L, Forsberg P, Smedby O| title=Brain magnetic resonance imaging does not contribute to the diagnosis of chronic neuroborreliosis. | journal=Acta Radiol | year= 2007 | volume= 48 | issue= 7 | pages= 755-62 | pmid=17729007 | doi=10.1080/02841850701367903 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17729007 }}</ref>
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| * [[Magnetic resonance imaging|MRI]] scans of patients with [[Neurology|neurologic]] manifestation of [[Lyme disease]] may demonstrate increased intensity in [[white matter]] at multiple foci on T2-weighted images suggesting [[demyelination]] or [[Inflammation|inflammatory]] changes.<ref name="pmid1476570">{{cite journal| author=Belman AL, Coyle PK, Roque C, Cantos E| title=MRI findings in children infected by Borrelia burgdorferi. | journal=Pediatr Neurol | year= 1992 | volume= 8 | issue= 6 | pages= 428-31 | pmid=1476570 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1476570 }}</ref>
| | ==Tables== |
| *These changes are similar to those seen in [[demyelinating]] or [[inflammatory]] disorders such as [[multiple sclerosis]] or [[systemic lupus erythematosus]] (SLE).<ref name="pmid9774805">{{cite journal| author=Fallon BA, Kochevar JM, Gaito A, Nields JA| title=The underdiagnosis of neuropsychiatric Lyme disease in children and adults. | journal=Psychiatr Clin North Am | year= 1998 | volume= 21 | issue= 3 | pages= 693-703, viii | pmid=9774805 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9774805 }} </ref>
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| * [[Magnetic resonance imaging|MRI]] scan of a few patients with [[Neurology|neurologic]] manifestation of [[Lyme disease]] may show [[cerebral atrophy]] and brainstem [[neoplasm]].<ref>{{cite journal|author=Kalina P, Decker A, Kornel E, Halperin JJ|title=Lyme disease of the brainstem|journal=Neuroradiology|volume=47|issue=12|pages=903-7|year=2005|pmid=16158278|doi=10.1007/s00234-005-1440-2}}</ref>
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| * [[Magnetic resonance imaging|MRI]] scan of a few patients with [[Bell's palsy|facial palsy]] may show enhancement of [[facial nerve]].<ref name="pmid9860125">{{cite journal| author=Vanzieleghem B, Lemmerling M, Carton D, Achten E, Vanlangenhove P, Matthys E et al.| title=Lyme disease in a child presenting with bilateral facial nerve palsy: MRI findings and review of the literature. | journal=Neuroradiology | year= 1998 | volume= 40 | issue= 11 | pages= 739-42 | pmid=9860125 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9860125 }} </ref>
| | !Diagnosis |
| *Diffuse [[white matter]] pathology can disrupt these ubiquitous [[gray matter]] connections and could account for deficits in [[attention]], [[memory]], visuospatial ability, complex [[cognition]], and [[emotional]] status.
| | !Lab findings |
| *[[White matter]] disease may have a greater potential for recovery than [[Grey matter|gray matter]] disease, perhaps because neuronal loss is less common in white matter disease.
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| *After [[antibiotic therapy]], spontaneous resolution of [[MRI]] [[white matter]] hyper-intensities has been observed in [[Lyme disease]].<ref>{{cite journal |author=Fallon BA, Keilp J, Prohovnik I, Heertum RV, Mann JJ |title=Regional cerebral blood flow and cognitive deficits in chronic lyme disease |journal=The Journal of neuropsychiatry and clinical neurosciences |volume=15 |issue=3 |pages=326-32 |year=2003 |pmid=12928508}}</ref>
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| ==References== | | ==References== |
| {{reflist|2}} | | {{reflist|2}} |
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| [[Category:Needs overview]]
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| [[Category:Bacterial diseases]]
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| [[Category:Insect-borne diseases]]
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| [[Category:Lyme disease]]
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| [[Category:Zoonoses]]
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| [[Category:Spirochaetes]]
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| [[Category:Disease]]
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| [[Category:Infectious disease]]
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| [[Category:Dermatology]]
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| [[Category:Emergency medicine]]
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| [[Category:Intensive care medicine]]
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