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{{CMG}}; {{AE}} {{AKI}}
{{Roseola}}
{{CMG}}:{{AE}}{{DAMI}}


==Overview==


==Historical Perspective==
==[[Roseola overview|Overview]]==


==Classification==
==[[Roseola historical perspective|Historical Perspective]]==


==Pathophysiology==
==[[Roseola classification|Classification]]==


===Pathogenesis===
==[[Roseola pathophysiology|Pathophysiology]]==
*Necrotizing ulcerative gingivitis presents with inter-dental gingival necrosis, which is described as "punched out" ulcerated papillae, gingival bleeding and pain.
*NUG affects the interdental and marginal soft tissue and has minimal osseous involvement when compared to periodontitis.


===Microscopic Pathology===
==[[Roseola causes|Causes]]==
*The features characteristic of NUG on microscopic examination include neutrophil rich, necrotic, and spirochetal infiltration zones are unique to NUG.
*Under electron microscopy, four zones are described and they include:
**'''Bacterial zone: ''' This zone demonstrates many different morphological types of high bacterial load, including the presence of spirochetes.
**'''Neutrophil rich zone:''' Below the bacterial zone, a neutrophil rich zone is demonstrated.
**'''Necrotic zone:''' This zone demonstrates disintegrated cells, with the presence of spirochetes and fusiform bacteria.
**'''Spirochete infilteration zone:''' The zone demonstrates tissues infiltrated by spirochetes which are present in high number. Absence of other other bacteria is characteristic.


==Causes==
==[[Roseola differential diagnosis|Differentiating Any Disease from other Diseases]]==
NUG is a polybacterial infection and the exact causative organisms are not identified, however the following organisms have been identified in most of the patients. The following is a list of organisms are associated with NUG, the presence of these organisms doesnot always help to make the diagnosis of NUG.
*Prevotella intermedia
*Fusobacterium sp
*Treponema - T. vincentii and T. buccalis
*Selenomonas sp.


==Epidemiology and Demographics==
==[[Roseola epidemiology and demographics|Epidemiology and Demographics]]==


==Natural History, Complications and Prognosis==
==[[Roseola risk factors|Risk Factors]]==  


==Diagnosis==
==[[Roseola screening|Screening]]==  


===History and Symptoms===
==[[Roseola natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
To make the diagnosis of NUG the traid of interproximal necrosis, bleeding, and pain must be present. Absence of any one of the features rules out the diagnosis of NUG.
====More common symptoms====
*Gingival bleeding
*Severe gingival pain
====Less common symptoms====
*Lymphadenopathy
*Bad breath-[[halitosis]]
*Fever
*Malaise


===Physical Examination===
==Diagnosis==
 
[[Roseola history and symptoms|History and Symptoms]] | [[Roseola physical examination|Physical Examination]] | [[Roseola laboratory findings|Laboratory Findings]] | [[Roseola electrocardiogram|Electrocardiogram]] | [[Roseola chest x ray|Chest X Ray]] | [[Roseola CT|CT]] | [[Roseola MRI|MRI]] | [[Roseola echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Roseola other imaging findings|Other Imaging Findings]] | [[Roseola other diagnostic studies|Other Diagnostic Studies]]
===Laboratory Findings===


==Treatment==
==Treatment==
===Medical Therapy===
[[Roseola medical therapy|Medical Therapy]] | [[Roseola surgery|Surgery]] | [[Roseola primary prevention|Primary Prevention]] | [[Roseola secondary prevention|Secondary Prevention]] | [[Roseola cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Roseola future or investigational therapies|Future or Investigational Therapies]]
 
===Surgical Therapy===


==Prevention==
==Case Studies==
===Primary Prevention===
[[Roseola case study one|Case #1]]
===Secondary Prevention===
==References==
{{Reflist|2}}

Latest revision as of 19:04, 22 May 2017


Roseola Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Roseola from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]:Associate Editor(s)-in-Chief: Omodamola Aje B.Sc, M.D. [2]


Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Any Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

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