Sandbox: HTM

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Common Medical Term OMIM Number Enzyme Gene location Substrates Products

21-hydroxylase CAH

Online Mendelian Inheritance in Man (OMIM) 201910
P450c21
6p21.3
17OH-progesterone→
Progesterone
11-deoxycortisol→
DOC

lipoid CAH
(20,22-desmolase)

Online Mendelian Inheritance in Man (OMIM) 201710
StAR
P450scc
8p11.2
15q23-q24
Transport of cholesterol
cholesterol
Into mitochondria→
Pregnenolone

17α-hydroxylase CAH

Online Mendelian Inheritance in Man (OMIM) 202110
P450c17
10q24.3
pregnenolone
progesterone
17OH-pregnenolone→
17OH-pregnenolone
17OH-progesterone
DHEA

3β-HSD CAH

Online Mendelian Inheritance in Man (OMIM) 201810
3βHSD II
1p13
Pregnenolone
17OH-pregnenolone→
DHEA
Progesterone
17OH-progesterone
androstenedione

11β-hydroxylase CAH

Online Mendelian Inheritance in Man (OMIM) 202010
P450c11β
8q21-22
11-deoxycortisol→
DOC→
Cortisol
Corticosterone