Sandbox:MDS

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Name Description
Refractory anemia
  • Less than 5% primitive blood cells (myeloblasts) in the bone marrow and pathological abnormalities primarily seen in red cell precursors.
Refractory anemia with ring sideroblasts (RARS)|
  • Less than 5% myeloblasts in the bone marrow, but distinguished by the presence of 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.
Refractory anemia with excess blasts (RAEB)
  • 5-20% myeloblasts in the marrow.
Refractory anemia with excess blasts in transformation (RAEB-T)
  • 21-30% myeloblasts in the marrow (>30% blasts is defined as acute myeloid leukemia).
Chronic myelomonocytic leukemia (CMML)
  • Less than 20% myeloblasts in the bone marrow and greater than 1*109/L monocytes in peripheral blood.



Old system New system
Refractory anemia|

Refractory cytopenia with unilineage dysplasia

Refractory anemia with ringed sideroblasts

Refractory anemia with ring sideroblasts

Refractory cytopenia with multilineage dysplasia

Refractory anemia with excess blasts

Refractory anemias with excess blasts I and II

Refractory anemia with excess blasts in transformation I–IV |

5q - syndrome

Chronic myelomonocytic leukemia|

Myelodysplastic-myeloproliferative overlap syndromes

Refractory cytopenia of childhood

Unclassifiable myelodysplastic syndrome