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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]


Overview

The Spleen is the most commonly affected organ in the abdomen leading to splenectomy as a result of blunt trauma to the abdomen.The trauma can be due to number of reasons such as road side accidents,falls,violence.There are a number of non traumatic reasons of splenic rupture due to an underlying pathology.

Classification

Historical Perspective

Pathophysiology

Causes

Common casuses

The common causes of splenic rupture includes.[1]

  • Neoplasms
  • Infections
  • Non Infectious
  • Therapy related
  • Mechanical Causes


Less common casuses

  • Autologus stem cell transplantation in AL Amyloidosis patients[2]

Differentiating Splenic Rupture from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-Ray

MRI

Other Imaging Findings

Other Diagnostic Studies

References

  1. Renzulli P, Hostettler A, Schoepfer AM, Gloor B, Candinas D (2009). "Systematic review of atraumatic splenic rupture". Br J Surg. 96 (10): 1114–21. doi:10.1002/bjs.6737. PMID 19787754.
  2. Sato S, Tamai Y, Okada S, Kannbe E, Takeda K, Tanaka E (2017). "Atraumatic Splenic Rupture due to Ectopic Extramedullary Hematopoiesis after Autologous Stem Cell Transplantation in a Patient with AL Amyloidosis". Intern Med. doi:10.2169/internalmedicine.9018-17. PMID 29093392.