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==Classification==
==Classification==
*Restless leg syndrome (RLS), may be classified into two groups:<ref name="pmid18360657">{{cite journal| author=Cotter PE, O'Keeffe ST| title=Restless leg syndrome: is it a real problem? | journal=Ther Clin Risk Manag | year= 2006 | volume= 2 | issue= 4 | pages= 465-75 | pmid=18360657 | doi= | pmc=1936366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18360657  }} </ref>
Restless leg syndrome (RLS), may be classified into two groups:<ref name="pmid18360657">{{cite journal| author=Cotter PE, O'Keeffe ST| title=Restless leg syndrome: is it a real problem? | journal=Ther Clin Risk Manag | year= 2006 | volume= 2 | issue= 4 | pages= 465-75 | pmid=18360657 | doi= | pmc=1936366 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18360657  }} </ref>
**Primary and secondary:
*Primary and secondary:
*** Primary RLS is [[idiopathic]] and the cause of that is unknown which is familial in up to two thirds of patients. Primary RLS usually begins before approximately 40 to 45 years of age, and can even occur as early as the first year of life.  In primary RLS, the onset is often slow.
** Primary RLS is [[idiopathic]] and the cause of that is unknown which is familial in up to two thirds of patients. Primary RLS usually begins before approximately 40 to 45 years of age, and can even occur as early as the first year of life.  In primary RLS, the onset is often slow.
***Secondary RLS may also be secondary to a number of conditions including:
**Secondary RLS may also be secondary to a number of conditions including:
****iron deficiency, pregnancy and end-stage renal failure and, perhaps, neuropathy. Secondary RLS is most common in those presenting for the first time in later life
***[[Iron deficiency anemia|Iron deficiency]]
 
***[[Pregnancy]]
OR
***[[End-stage renal failure]]
*[Disease name] may be classified into [large number > 6] subtypes based on:
***[[varicose vein]]
**[Classification method 1]
***Venous reflux
**[Classification method 2]
***[[folate deficiency]]
**[Classification method 3]
***[[sleep apnea]]
*[Disease name] may be classified into several subtypes based on:
***[[uremia]]
**[Classification method 1]
***[[diabetes mellitus|Diabetes]]
**[Classification method 2]
***Thyroid problems
**[Classification method 3]
***Peripheral neuropathy
OR
***[[Parkinson's disease]]
*Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
***Certain [[auto-immune disorders]] such as:
OR
****[[Sjögren's syndrome]],  
*If the staging system involves specific and characteristic findings and features:
****[[Celiac Disease]]
*According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
****[[rheumatoid arthritis]].  
OR
**Secondary RLS is most common in those presenting for the first time in later life.
*The staging of [malignancy name] is based on the [staging system].
OR
*There is no established system for the staging of [malignancy name].
==Classification==
RLS is either primary or secondary.
*  
 
===Secondary===
* Secondary RLS often has a sudden onset and may be daily from the very beginning. It often occurs after the age of 40, however it can occur earlier.  It is most associated with specific medical conditions or the use of certain drugs. The most commonly associated medical condition is [[iron deficiency (medicine)|iron deficiency]], which accounts for just over 20% of all cases of RLS.  The conditions include: pregnancy, [[varicose vein]] or venous reflux, [[folate deficiency]], [[sleep apnea]], [[uremia]], [[diabetes mellitus|diabetes]], thyroid problems, peripheral neuropathy, [[Parkinson's disease]] and certain auto-immune disorders such as [[Sjögren's syndrome]], [[Celiac Disease]], and [[rheumatoid arthritis]]. Treatment of the underlying condition, or cessation of use of the offending drug, often eliminates the RLS.
 
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 18:28, 27 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Classification

Restless leg syndrome (RLS), may be classified into two groups:[1]

References

  1. Cotter PE, O'Keeffe ST (2006). "Restless leg syndrome: is it a real problem?". Ther Clin Risk Manag. 2 (4): 465–75. PMC 1936366. PMID 18360657.

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