Psittacosis laboratory tests: Difference between revisions

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* Macroscopically they have patchy consolidation.
* Macroscopically they have patchy consolidation.
* Microscopically exudation and interstitial changes are seen.
* Microscopically exudation and interstitial changes are seen.
* They are best seen with Giemsa stain.
* They are best seen with Giemsa stain as inclusions called '''Leventhal -Colle-Lillie bodies''' and can be seen within macrophages in BAL fluid.


===Culture===
===Culture===

Revision as of 19:03, 7 August 2012

Psittacosis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

Exposure history is paramout to diagnosis. Bloodwork shows leukopenia, thrombocytopenia and moderately elevated liver enzymes.

Laboratory Findings

Electrolyte and Biomarker Studies

  • Leukocytosis
  • Rise in ESR
  • Rise in CRP
  • Liver enzymes elevated
  • Hyponatremia may be noticed
  • Rise in blood urea levels
  • Urinalysis may show proteinuria

Chest X Ray

  • Lobar consolidation may be seen
  • Infiltrates may be evidenced

CT Scan

  • On high resolution CT , infiltrates may be nodular and surrounded by ground glass opacity.[1]

Biopsy

  • Macroscopically they have patchy consolidation.
  • Microscopically exudation and interstitial changes are seen.
  • They are best seen with Giemsa stain as inclusions called Leventhal -Colle-Lillie bodies and can be seen within macrophages in BAL fluid.

Culture

Serology

  • A fourfold or greater increase in antibody titers are against the diagnosis of C. psittaci in blood samples combined with the probable course of the disease.
Culture of Chlamydia psittaci is hazardous and should only be carried out in biosafety laboratories.

References

  1. Hochhegger B, Marchiori E, Irion KL, Santos de Melo G, Mendes F, Zanetti G (2009). "Psittacosis presenting as a halo sign on high-resolution computed tomography". J Thorac Imaging. 24 (2): 136–7. doi:10.1097/RTI.0b013e318191987e. PMID 19465839. Unknown parameter |month= ignored (help)


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