Psittacosis laboratory tests: Difference between revisions
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===CT Scan=== | ===CT Scan=== | ||
* On high resolution CT , infiltrates may be nodular and surrounded by ground glass opacity.<ref name="pmid19465839">{{cite journal |author=Hochhegger B, Marchiori E, Irion KL, Santos de Melo G, Mendes F, Zanetti G |title=Psittacosis presenting as a halo sign on high-resolution computed tomography |journal=J Thorac Imaging |volume=24 |issue=2 |pages=136–7 |year=2009 |month=May |pmid=19465839 |doi=10.1097/RTI.0b013e318191987e |url=}}</ref> | * On high resolution CT , infiltrates may be nodular and surrounded by ground glass opacity.<ref name="pmid19465839">{{cite journal |author=Hochhegger B, Marchiori E, Irion KL, Santos de Melo G, Mendes F, Zanetti G |title=Psittacosis presenting as a halo sign on high-resolution computed tomography |journal=J Thorac Imaging |volume=24 |issue=2 |pages=136–7 |year=2009 |month=May |pmid=19465839 |doi=10.1097/RTI.0b013e318191987e |url=}}</ref> | ||
===Biopsy=== | |||
* Macroscopically they have patchy consolidation. | |||
* Microscopically exudation and interstitial changes are seen. | |||
*hey are best seen with Giemsa stain. | |||
Diagnosis involves [[microbiological culture]]s from respiratory secretions of patients or [[serology|serologically]] with a fourfold or greater increase in [[antibody]] titers against ''C. psittaci'' in blood samples combined with the probable course of the disease. Typical inclusions called Leventhal -Colle-Lillie bodies can be seen within macrophages in BAL fluid. Culture of Chlamydia psittaci is hazardous and should only be carried out in biosafety laboratories. | Diagnosis involves [[microbiological culture]]s from respiratory secretions of patients or [[serology|serologically]] with a fourfold or greater increase in [[antibody]] titers against ''C. psittaci'' in blood samples combined with the probable course of the disease. Typical inclusions called Leventhal -Colle-Lillie bodies can be seen within macrophages in BAL fluid. Culture of Chlamydia psittaci is hazardous and should only be carried out in biosafety laboratories. |
Revision as of 18:57, 7 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Exposure history is paramout to diagnosis. Bloodwork shows leukopenia, thrombocytopenia and moderately elevated liver enzymes.
Laboratory Findings
Electrolyte and Biomarker Studies
- Leukocytosis
- Rise in ESR
- Rise in CRP
- Liver enzymes elevated
- Hyponatremia may be noticed
- Rise in blood urea levels
- Urinalysis may show proteinuria
Chest X Ray
- Lobar consolidation may be seen
- Infiltrates may be evidenced
CT Scan
- On high resolution CT , infiltrates may be nodular and surrounded by ground glass opacity.[1]
Biopsy
- Macroscopically they have patchy consolidation.
- Microscopically exudation and interstitial changes are seen.
- hey are best seen with Giemsa stain.
Diagnosis involves microbiological cultures from respiratory secretions of patients or serologically with a fourfold or greater increase in antibody titers against C. psittaci in blood samples combined with the probable course of the disease. Typical inclusions called Leventhal -Colle-Lillie bodies can be seen within macrophages in BAL fluid. Culture of Chlamydia psittaci is hazardous and should only be carried out in biosafety laboratories.