Psittacosis laboratory tests: Difference between revisions
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== Laboratory Findings== | == Laboratory Findings== | ||
===Electrolyte and Biomarker Studies=== | ===Electrolyte and Biomarker Studies<ref name="pmid2401812">{{cite journal| author=Kuwabara M, Tanemori N, Kawaguti Y, Nakamura K, Nomiyama S, Terada M et al.| title=[Clinical features of 36 cases of psittacosis]. | journal=Kansenshogaku Zasshi | year= 1990 | volume= 64 | issue= 4 | pages= 498-503 | pmid=2401812 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2401812 }} </ref><ref name="pmid3062725">{{cite journal| author=Sahn SA| title=Pleural effusions in the atypical pneumonias. | journal=Semin Respir Infect | year= 1988 | volume= 3 | issue= 4 | pages= 322-34 | pmid=3062725 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3062725 }} </ref>=== | ||
* [[Leukocytosis]] | * [[Leukocytosis]] | ||
* Rise in [[ESR]] | * Rise in [[ESR]] |
Revision as of 15:54, 10 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]Omodamola Aje B.Sc, M.D. [3]
Overview
Exposure history is paramount to diagnosis. Complete blood count shows leukopenia, thrombocytopenia and moderately elevated liver enzymes.
Laboratory Findings
Electrolyte and Biomarker Studies[1][2]
- Leukocytosis
- Rise in ESR
- Rise in CRP[3]
- Liver enzymes elevated
- Rise in creatinine kinase[4]
- Hyponatremia may be noticed
- Rise in blood urea nitrogen levels
- Urinalysis may show proteinuria
Culture
- Culture of C. psittaci is demanding, requires a level 3 laboratory isolation facility because of the risk of laboratory transmission and is rarely performed.
- Microbiological cultures from respiratory secretions.
- Culture of Chlamydia psittaci is hazardous and should only be carried out in bio safety laboratories.
- It is tedious process and seldom done.
Serology
- A fourfold or greater increase in antibody titers are against the diagnosis of C. psittaci in blood samples combined with the probable course of the disease.
- Serology is the most widely available method for laboratory diagnosis of C. psittaci infection. Complement fixation, microimmunofluorescence, and EIA the most commonly used techniques.
Nucleic Acid Amplification
PCR techniques have been utilized in outbreaks for several years and can give a rapid, specific diagnosis, which is particularly important in severe infection.
References
- ↑ Kuwabara M, Tanemori N, Kawaguti Y, Nakamura K, Nomiyama S, Terada M; et al. (1990). "[Clinical features of 36 cases of psittacosis]". Kansenshogaku Zasshi. 64 (4): 498–503. PMID 2401812.
- ↑ Sahn SA (1988). "Pleural effusions in the atypical pneumonias". Semin Respir Infect. 3 (4): 322–34. PMID 3062725.
- ↑ Yung AP, Grayson ML (1988). "Psittacosis--a review of 135 cases". Med J Aust. 148 (5): 228–33. PMID 3343952.
- ↑ Crosse BA (1990). "Psittacosis: a clinical review". J Infect. 21 (3): 251–9. PMID 2273272.