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| __NOTOC__
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| {{Protriptyline}}
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| {{CMG}}; {{AE}} {{PB}}
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| '''''For patient information about Protriptyline, click [[Protriptyline (patient information)|here]].'''''
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| {{SB}} Vivactil®<sup>®</sup>
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| ==Overview==
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| {{drugbox |
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| | IUPAC_name = ''N''-Methyl-''5H''-dibenzo[a,d]cycloheptene-5-propanamine
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| | image = Protriptyline.png
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| | CAS_number = 438-60-8
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| | ATC_prefix = N06
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| | ATC_suffix = AA11
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| | PubChem = 4976
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| | DrugBank =
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| | C=19|H=21|N=1
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| | molecular_weight = 263.377 g/mol
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| | bioavailability =
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| | protein_bound =
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| | metabolism = [[Hepatic]]
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| | elimination_half-life = 54-92 hours
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| | excretion = [[Renal]], in urine
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| | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
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| | pregnancy_US = C
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| | pregnancy_category=
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| | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
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| | legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII -->
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| | legal_UK = <!-- GSL / P / POM / CD / Class A, B, C -->
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| | legal_US =
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| | legal_status = Schedule VI<small> (US)</small>
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| | routes_of_administration = Oral
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| }}
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| '''Protriptyline''' is a [[tricyclic antidepressant]] (TCA), specifically a [[secondary amine]], indicated for depression and ADHD. Unique among the tricyclics, protriptyline tends to be energizing instead of sedating, and it is sometimes used in narcolepsy to achieve a wakefulness-promoting effect.{{Fact|date=November 2007}} (The other TCAs tend to be sedating and therefore are often taken in the evening.)
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| Tricyclics including protriptyline are also used to reduce the incidence of recurring headaches such as migraine, and for other types of chronic pain.
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| ==Category==
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| ==FDA Package Insert==
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| ==VIVACTIL (protriptyline hydrochloride) tablet==
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| ''' [[VIVACTIL (protriptyline hydrochloride) tablet indications and usage|Indications and Usage]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet dosage and administration|Dosage and Administration]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet dosage forms and strengths|Dosage Forms and Strengths]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet contraindications|Contraindications]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet warnings and precautions|Warnings and Precautions]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet adverse reactions|Adverse Reactions]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet drug interactions|Drug Interactions]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet use in specific populations|Use in Specific Populations]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet overdosage|Overdosage]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet description|Description]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet clinical pharmacology|Clinical Pharmacology]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet nonclinical toxicology|Nonclinical Toxicology]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet clinical studies|Clinical Studies]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet how supplied storage and handling|How Supplied/Storage and Handling]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet patient counseling information|Patient Counseling Information]]'''
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| '''| [[VIVACTIL (protriptyline hydrochloride) tablet labels and packages|Labels and Packages]]'''
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| ==Mechanism of Action==
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| <ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = VIVACTIL (PROTRIPTYLINE HYDROCHLORIDE) TABLET, FILM COATED [TEVA WOMEN'S HEALTH, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=6ea1b78e-acf4-4cd6-a126-699a0567669a | publisher = | date = | accessdate = }}</ref>
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| ==References==
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| {{Reflist|2}}
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| {{Antimigraine preparations}}
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| [[Category:Drugs]]
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| {{Antidepressants}}
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| [[Category:Tricyclic antidepressants]]
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| {{pharma-stub}}
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