Prolactinoma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2], Faizan Sheraz, M.D. [3]

Overview

MRI may be diagnostic of prolactinoma. Magnetic resonance imaging (MRI) is the most sensitive test for detecting pituitary tumors and determining their size.

Key MRI findings in prolactinoma

MRI may be diagnostic of prolactinoma. Magnetic resonance imaging (MRI) is the most sensitive test for detecting pituitary tumors and determining their size. Contrast enhanced MRIs have a sensitivity of 90%. Findings on MRI scans suggestive of prolactinoma include:[1]

MRI Component Features
T1​
  • Usually isointense to normal pituitary
T1 C+ (Gd)
  • Dynamic sequences demonstrate a rounded region of delayed enhancement compared to the rest of the gland
  • Delayed images are variable, ranging from hypo-enhancement (most common), to isointense to the rest of the gland, to hyperintense (retained contrast)
T2
  • Variable, but often a little hyperintense

MRI examples of Prolactinoma

Coronal T1 contrast enhanced MRI showing microadenoma[1]

Saggital T1 contrast enhanced MRI showing macroadenoma[1]

References

  1. 1.0 1.1 1.2 "Pituitary microadenoma | Radiology Reference Article | Radiopaedia.org".


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