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'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''.
__NOTOC__
 
{{DiseaseDisorder infobox |
  Name          = Prolactinoma |
  ICD10          = {{ICD10|D|35|2|d|10}} |
  ICD9          = {{ICD9|253.1}} |
  ICDO          = 8271/0|
  Image          = |
  Caption        = |
  OMIM          = 600634 |
  OMIM_mult      = |
  MedlinePlus    = |
  DiseasesDB    = 10735 |
}}
{{Prolactinoma}}
{{Prolactinoma}}
{{CMG}}
==[[Prolactinoma overview|Overview]]==


==[[Prolactinoma epidemiology and demographics|Epidemiology & Demographics]]==
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


==[[Prolactinoma causes|Causes of Prolactinoma]]==
{{CMG}}; {{AE}} {{Anmol}}, {{Faizan}}


==[[Prolactinoma history and symptoms|History & Symptoms]]==
{{SK}} Prolactin secreting pituitary adenoma, lactotroph adenoma, prolactin cell adenoma, prolactin secreting adenoma, prolactin cell tumor


== Diagnosis ==
==[[Prolactinoma overview|Overview]]==


==[[Prolactinoma physical examination|Physical Examination]]==
==[[Prolactinoma historical perspective|Historical Perspective]]==


==[[Prolactinoma laboratory tests|Lab Tests]]==
==[[Prolactinoma classification|Classification]]==


==[[Prolactinoma MRI|MRI]]==
==[[Prolactinoma pathophysiology|Pathophysiology]]==


==[[Prolactinoma CT|CT]]==
==[[Prolactinoma causes|Causes]]==


== Treatments ==
==[[Prolactinoma differential diagnosis|Differentiating Prolactinoma from other Diseases]]==
The goal of treatment is to return prolactin secretion to normal, reduce tumor size, correct any visual abnormalities, and restore normal pituitary function. As mentioned above, the impact of stress should be ruled out before the diagnosis of prolactinoma is given.  Exercise can significantly reduce stress and, thereby, prolactin levels.  It should also be noted that higher prolactin levels may contribute to the development of prolactinomas so the diagnosis can be self-fulfilling if the original cause is stress. In the case of very large tumors, only partial reduction of the prolactin levels may be possible.


==[[Prolactinoma medical therapy|Medical Therapy]]==
==[[Prolactinoma epidemiology and demographics|Epidemiology and Demographics]]==


==[[Prolactinoma surgery|Surgery]]==
==[[Prolactinoma risk factors|Risk Factors]]==


==[[Prolactinoma natural history, complications, and prognosis|Natural history, Complications, and Prognosis]]==
==[[Prolactinoma Screening|Screening]]==


== Osteoporosis Risk ==
==[[Prolactinoma natural history, complications, and prognosis|Natural History, Complications and Prognosis]]==
[[Hyperprolactinemia]] can cause reduced [[estrogen]] production in women and reduced [[testosterone]] production in men.  Although estrogen/testosterone production may be restored after treatment for hyperprolactinemia, even a year or two without estrogen/testosterone can compromise bone strength, and patients should protect themselves from osteoporosis by increasing exercise and [[calcium]] intake through diet or supplementation, and by avoiding smoking. Patients may want to have bone density measurements to assess the effect of estrogen/testosterone deficiency on bone density. They may also want to discuss testosterone/estrogen replacement therapy with their physician.


== Prognosis ==
==Diagnosis==
People with microprolactinoma generally have an excellent prognosis.  In 95% of cases the tumor will not show any signs of growth after a 4 to 6 year period.


Macroprolactinomas often require more aggressive treatment otherwise they may continue to grow. There is no way to reliably predict the rate of growth, as it is different for every individual.  Regular monitoring by a specialist to detect any major changes in the tumor is recommended.
[[Prolactinoma history and symptoms|History and Symptoms ]] | [[ Prolactinoma physical examination|Physical Examination]] | [[Prolactinoma laboratory tests|Laboratory Findings]] | [[Prolactinoma ECG|ECG]] | [[Prolactinoma X-ray|X-ray]]| [[Prolactinoma ultrasound|Ultrasound]] | [[Prolactinoma CT|CT]] | [[Prolactinoma MRI|MRI]] | [[Prolactinoma other imaging findings|Other Imaging Findings]] | [[Prolactinoma other diagnostic studies|Other Diagnostic Studies]]


== References ==
==Treatment==
Adapted from '''Prolactinoma'''. U. S. National Institutes of Health Publication No. 02-3924 June 2002. [http://www.niddk.nih.gov/health/endo/pubs/prolact/prolact.htm Public Domain Source]
[[Prolactinoma medical therapy|Medical Therapy]] | [[Prolactinoma surgery |Surgery]] |[[Prolactinoma primary prevention |Primary prevention]] |[[Prolactinoma secondary prevention |Secondary prevention]] | [[Prolactinoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] |  [[Prolactinoma future or investigational therapies|Future or Investigational Therapies]]


==External links==
==Case Studies==
*[http://www.pituitary.com/disorders/prolactinomas.aspx Pituitary Network Association]
 
*[http://www.pituitary.org.uk/resources/prolactinoma.htm The Pituitary Foundation]
[[Prolactinoma case study one|Case #1]]
*[http://www.endocrine.niddk.nih.gov/ Endocrine and Metabolic Diseases Information Service]


{{Epithelial neoplasms}}
{{Epithelial neoplasms}}


[[de:Prolaktinom]]


{{WikiDoc Help Menu}}
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{{WikiDoc Sources}}
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Neuroendocrinology]]
[[Category:Neuroendocrinology]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Mature chapter]]
[[Category:Medicine]]
[[Category:Endocrinology]]
[[Category:Up-To-Date]]
[[Category:Neurology]]
[[Category:Neurosurgery]]

Latest revision as of 23:49, 29 July 2020

Prolactinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Prolactinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

ECG

X-ray

Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Prolactinoma On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Prolactinoma

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Prolactinoma

CDC on Prolactinoma

Prolactinoma in the news

Blogs on Prolactinoma

Directions to Hospitals Treating Prolactinoma

Risk calculators and risk factors for Prolactinoma

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2], Faizan Sheraz, M.D. [3]

Synonyms and keywords: Prolactin secreting pituitary adenoma, lactotroph adenoma, prolactin cell adenoma, prolactin secreting adenoma, prolactin cell tumor

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Prolactinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | ECG | X-ray| Ultrasound | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery |Primary prevention |Secondary prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Template:Epithelial neoplasms


Template:WikiDoc Sources

​

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