Polio differential diagnosis: Difference between revisions

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| style="padding: 5px 5px; background: #DCDCDC;" | '''Traumatic [[neuritis]] of the [[sciatic nerve]]'''
| style="padding: 5px 5px; background: #DCDCDC;" | '''Traumatic [[neuritis]] of the [[sciatic nerve]]'''
| style="padding: 5px 5px; background: #F5F5F5;" | Often occurs few days after [[intramuscular]] injections, presenting with pain and decrease of temperature of the affected limb.  Unlike paralytic poliomyelitis, it has an injection as causative agent, and does not cause muscular atrophy, or [[skeletal]] deformities.
| style="padding: 5px 5px; background: #F5F5F5;" | Often occurs few days after [[intramuscular]] injections, presenting with pain and decreased temperature of the affected limb.  Unlike paralytic poliomyelitis, it has an injection as causative agent, and does not cause [[muscular]] atrophy, or [[skeletal]] deformities.
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| style="padding: 5px 5px; background: #DCDCDC;" |'''[[Transverse myelitis]]'''
| style="padding: 5px 5px; background: #DCDCDC;" |'''[[Transverse myelitis]]'''
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" | Often presents as symmetrical, flaccid paresis, decreased sensory level and neurogenic bladder.  Unlike paralytic poliomyelitis, it does not cause skeletal deformities.
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| style="padding: 5px 5px; background: #DCDCDC;" |'''[[West Nile Virus]]'''
| style="padding: 5px 5px; background: #DCDCDC;" |'''[[West Nile Virus]]'''
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TNC presents several days after IM injections with pain and hypothermia in the affected limbs; TM is a flaccid, symmetrical paraparesis with neurogenic bladder and a sensory level. CSF and neurophysiological studies (EMG and NCV) are very useful for diagnosis. Other entities misdiagnosed as poliomyelitis were: osteoarticular trauma, myopathies and dystrophies, viral myositis, acute cerebellitis, retroperitoneal tumors and upper motor neuron syndromes. Viral studies in stool specimens are essential for the diagnosis of poliomyelitis
CSF and neurophysiological studies (EMG and NCV) are very useful for diagnosis. Other entities misdiagnosed as poliomyelitis were: osteoarticular trauma, myopathies and dystrophies, viral myositis, acute cerebellitis, retroperitoneal tumors and upper motor neuron syndromes. Viral studies in stool specimens are essential for the diagnosis of poliomyelitis
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Revision as of 22:51, 1 September 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

Abortive poliomyelitis must be differentiated from other diseases that cause: fever, nausea, vomiting, diarrhea, headache and sore throat, such as: gastroenteritis, or acute respiratory infection.[1][2]

Non-paralytic poliomyelitis must be differentiated from other diseases that cause: fever; headache; myalgia; vomiting; lethargy; and muscle spasms, such as:[2][3]

Paralytic poliomyelitis must be differentiated from other diseases that cause: headache, muscle pain; lethargy, muscle weakness, spams and tremors, such as: Guillain-Barré syndrome; traumatic neuritis of the sciatic nerve; transverse myelitis; and West Nile Virus.[2][4][5][6][7][8]

Differential Diagnosis

Abortive Poliomyelitis

Disease Findings
Gastroenteritis
Acute respiratory infection

Non-Paralytic Poliomyelitis

Disease Findings
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'
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Paralytic Poliomyelitis

The table below summarizes the findings that differentiate poliomyelitis from other conditions that cause headache, muscle pain; lethargy, muscle weakness, spams and tremors:[2][9][5][6][7][8]

Disease Findings
Guillain-Barré syndrome Often presents with distal, ascending, symmetrical paralysis with abolished reflexes. Unlike paralytic poliomyelitis, it does not cause muscular atrophy, or skeletal deformities.
Traumatic neuritis of the sciatic nerve Often occurs few days after intramuscular injections, presenting with pain and decreased temperature of the affected limb. Unlike paralytic poliomyelitis, it has an injection as causative agent, and does not cause muscular atrophy, or skeletal deformities.
Transverse myelitis Often presents as symmetrical, flaccid paresis, decreased sensory level and neurogenic bladder. Unlike paralytic poliomyelitis, it does not cause skeletal deformities.
West Nile Virus
Encephalitis


References

  1. Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.
  2. 2.0 2.1 2.2 2.3 Sutter RW, Brink EW, Cochi SL, Kew OM, Orenstein WA, Biellik RJ; et al. (1989). "A new epidemiologic and laboratory classification system for paralytic poliomyelitis cases". Am J Public Health. 79 (4): 495–8. PMC 1349984. PMID 2929811.
  3. Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.
  4. Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.
  5. 5.0 5.1 Alcalá H (1993). "[The differential diagnosis of poliomyelitis and other acute flaccid paralyses]". Bol Med Hosp Infant Mex. 50 (2): 136–44. PMID 8442872.
  6. 6.0 6.1 Asnis DS, Conetta R, Teixeira AA, Waldman G, Sampson BA (2000). "The West Nile Virus outbreak of 1999 in New York: the Flushing Hospital experience". Clin Infect Dis. 30 (3): 413–8. doi:10.1086/313737. PMID 10722421.
  7. 7.0 7.1 Campbell, Grant L; Marfin, Anthony A; Lanciotti, Robert S; Gubler, Duane J (2002). "West Nile virus". The Lancet Infectious Diseases. 2 (9): 519–529. doi:10.1016/S1473-3099(02)00368-7. ISSN 1473-3099.
  8. 8.0 8.1 Moorthi S, Schneider WN, Dombovy ML (1999). "Rehabilitation outcomes in encephalitis--a retrospective study 1990-1997". Brain Inj. 13 (2): 139–46. PMID 10079959.
  9. Falconer M, Bollenbach E (2000). "Late functional loss in nonparalytic polio". American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. 79 (1): 19–23. PMID 10678598.

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