Peptic ulcer epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ;Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Epidemiology and Demographics
A minority of cases of Helicobacter infection will eventually lead to an ulcer and a larger proportion of people will get non-specific discomfort, abdominal pain or gastritis. The prevalence of infection is greater in developing countries and is influenced by socioeconomic conditions, ethnic background and age.
Incidence
- The incidence of peptic ulcer disease is approximately 10-19 per 100,000 individuals worldwide.[1]
- In 2011, the incidence rate of peptic ulcer disease was estimated to be one case per 1000 individuals and peptic ulcer complications is 0.7 per 1000 individuals.[2]
- The incidence and prevalence of H. pylori infection are generally higher among people born outside North America. Within North America, the prevalence of the infection is higher in certain racial and ethnic groups, and people who have immigrated to North America
Prevalence
- The prevalence of peptic ulcer disease is approximately 23.1 per 100,000 individuals but higher in men 29.4 per 100,000 than women 14.9 per 100,000[3][1]
- The prevalence of peptic ulcer disease is estimated to be 4.5 million cases annually.[4][5]
- Lifetime prevalence is 11-14% in men and 8-11% in women
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Peptic ulcer disease is acquired during childhood.
- The incidence of Peptic ulcer disease increases with age; the median age at diagnosis is years.
- Peptic ulcer disease commonly affects individuals older women than younger men.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- Peptic ulcer disease usually affects individuals of the African Americans with a higher proportion of African ancestry race and Mexican Americans[6][7].Non-Hispanic whites individuals are less likely to develop the peptic ulcer disease.
Gender
- Peptic ulcer disease rates for male and female children are similar[8].
- Men are more commonly affected by peptic ulcer disease than women in adulhood[3].
The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
East Asia
Developed Countries
References
- ↑ 1.0 1.1 Sung JJ, Kuipers EJ, El-Serag HB (2009). "Systematic review: the global incidence and prevalence of peptic ulcer disease". Aliment. Pharmacol. Ther. 29 (9): 938–46. doi:10.1111/j.1365-2036.2009.03960.x. PMID 19220208.
- ↑ Lin KJ, García Rodríguez LA, Hernández-Díaz S (2011). "Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?". Pharmacoepidemiol Drug Saf. 20 (7): 718–28. doi:10.1002/pds.2153. PMID 21626606.
- ↑ 3.0 3.1 Naja F, Kreiger N, Sullivan T (2007). "Helicobacter pylori infection in Ontario: prevalence and risk factors". Can. J. Gastroenterol. 21 (8): 501–6. PMC 2657974. PMID 17703249.
- ↑ Kuipers EJ, Thijs JC, Festen HP (1995). "The prevalence of Helicobacter pylori in peptic ulcer disease". Aliment. Pharmacol. Ther. 9 Suppl 2: 59–69. PMID 8547530.
- ↑ Pounder RE, Ng D (1995). "The prevalence of Helicobacter pylori infection in different countries". Aliment. Pharmacol. Ther. 9 Suppl 2: 33–9. PMID 8547526.
- ↑ Nguyen T, Ramsey D, Graham D, Shaib Y, Shiota S, Velez M, Cole R, Anand B, Vela M, El-Serag HB (2015). "The Prevalence of Helicobacter pylori Remains High in African American and Hispanic Veterans". Helicobacter. 20 (4): 305–15. doi:10.1111/hel.12199. PMID 25689684.
- ↑ Everhart JE, Kruszon-Moran D, Perez-Perez GI, Tralka TS, McQuillan G (2000). "Seroprevalence and ethnic differences in Helicobacter pylori infection among adults in the United States". J. Infect. Dis. 181 (4): 1359–63. doi:10.1086/315384. PMID 10762567.
- ↑ de Martel C, Parsonnet J (2006). "Helicobacter pylori infection and gender: a meta-analysis of population-based prevalence surveys". Dig. Dis. Sci. 51 (12): 2292–301. doi:10.1007/s10620-006-9210-5. PMID 17089189.
- ↑ Siao D, Somsouk M (2014). "Helicobacter pylori: evidence-based review with a focus on immigrant populations". J Gen Intern Med. 29 (3): 520–8. doi:10.1007/s11606-013-2630-y. PMC 3930769. PMID 24065381.
- ↑ Perez-Perez GI, Olivares AZ, Foo FY, Foo S, Neusy AJ, Ng C, Holzman RS, Marmor M, Blaser MJ (2005). "Seroprevalence of Helicobacter pylori in New York City populations originating in East Asia". J Urban Health. 82 (3): 510–6. doi:10.1093/jurban/jti093. PMC 3456059. PMID 16033932.