Paraganglioma: Difference between revisions

	Paraganglioma Microchapters
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Revision as of 19:04, 20 January 2012

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

The main treatment modalities are surgery, embolization and radiotherapy.

@@ Line 19: / Line 19: @@
 ==[[Paraganglioma overview|Overview]]==
-==Inheritance==
+==[[Paraganglioma causes|Causes of Paraganglioma]]==
-Familial paragangliomas account for approx. 25% of cases, are often multiple and bilateral, and occur at an earlier age.  Mutations of the genes [[SDHD]] (previously known as PGL1), [[PGL2]], and [[SDHC (gene)|SDHC]] (previously PGL3) have been identified as causing familial head and neck paragangliomas. Mutations of [[SDHB]] play an important role in familial adrenal pheochromocytoma and extra-adrenal paraganglioma (of abdomen and thorax), although there is considerable overlap in the types of tumors associated with SDHB and SDHD gene mutations.
 ==[[Paraganglioma pathophysiology|Pathophysiology]]==