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__NOTOC__
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
{{Paraganglioma}}
{{Paraganglioma}}
{{CMG}} {{AE}} {{AAM}}


{{Infobox_Disease
{{SK}} Chemodectoma; Paraganglioma of the spine; Pulmonary paraganglioma; Carotid paraganglioma; Vagal paraganglioma
| Name          = {{PAGENAME}}
==[[Paraganglioma overview|Overview]]==
| Image          =
| Caption        =
| DiseasesDB    = 33480
| ICD10          =
| ICD9          =  
| ICDO          = 8680-8700
| OMIM          =  
| MedlinePlus    =  
| MeshID        =
}}
{{CMG}}


==[[Paraganglioma overview|Overview]]==
==[[Paraganglioma historical perspective|Historical Perspective]]==


==Inheritance==
==[[Paraganglioma classification|Classification]]==
Familial paragangliomas account for approx. 25% of cases, are often multiple and bilateral, and occur at an earlier age.  Mutations of the genes [[SDHD]] (previously known as PGL1), [[PGL2]], and [[SDHC (gene)|SDHC]] (previously PGL3) have been identified as causing familial head and neck paragangliomas. Mutations of [[SDHB]] play an important role in familial adrenal pheochromocytoma and extra-adrenal paraganglioma (of abdomen and thorax), although there is considerable overlap in the types of tumors associated with SDHB and SDHD gene mutations.


==[[Paraganglioma pathophysiology|Pathophysiology]]==
==[[Paraganglioma pathophysiology|Pathophysiology]]==


==[[Paraganglioma history and symptoms|History & Symptoms]]==
==[[Paraganglioma causes|Causes]]==
 
==[[Paraganglioma differential diagnosis|Differentiating Paraganglioma from other Diseases]]==
 
==[[Paraganglioma epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Paraganglioma risk factors|Risk Factors]]==
 
==[[Paraganglioma screening|Screening]]==
 
==[[Paraganglioma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
[[Paraganglioma diagnostic study of choice|Diagnostic study of choice]] | [[Paraganglioma history and symptoms|History and Symptoms]] | [[Paraganglioma physical examination|Physical Examination]] | [[Paraganglioma laboratory findings|Laboratory Findings]] | [[Paraganglioma electrocardiogram|Electrocardiogram]] | [[Paraganglioma x ray|X-Ray Findings]] | [[Paraganglioma echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Paraganglioma CT scan|CT-Scan Findings]] | [[Paraganglioma MRI|MRI Findings]] | [[Paraganglioma other imaging findings|Other Imaging Findings]] | [[Paraganglioma other diagnostic studies|Other Diagnostic Studies]]


==[[Paraganglioma medical therapy|Medical Therapy]]==
==Treatment==
The main treatment modalities are surgery, [[embolization]] and [[radiotherapy]].
[[Paraganglioma medical therapy|Medical Therapy]] | [[Paraganglioma surgery|Surgery]] | [[Paraganglioma primary prevention|Primary Prevention]] | [[Paraganglioma secondary prevention|Secondary Prevention]] | [[Paraganglioma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Paraganglioma future or investigational therapies|Future or Investigational Therapies]]


==References==
==Case Studies==
{{reflist|2}}
[[Paraganglioma case study one|Case #1]]
{{Epithelial neoplasms}}


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Latest revision as of 06:35, 28 July 2020

For patient information click here

Paraganglioma Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paraganglioma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT Scan

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Synonyms and keywords: Chemodectoma; Paraganglioma of the spine; Pulmonary paraganglioma; Carotid paraganglioma; Vagal paraganglioma

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paraganglioma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1